Copper level and metallothionein-like Cu-binding protein in cultured skin fibroblasts from patients with Menkes' disease and Wilson's disease

• Published in: No To Shinkei Vol. 36; no. 11; p. 1063
• Main Authors: Sato, M, Hayashi, A, Ito, H, Tojo, M, Arima, M
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.11.1984
• Subjects: Adolescent; Adult; Brain Diseases, Metabolic - metabolism; Carrier Proteins - metabolism; Cell Line; Cells, Cultured; Child; Chromatography, Gel; Copper - metabolism; Female; Fibroblasts - metabolism; Hepatolenticular Degeneration - metabolism; Hepatolenticular Degeneration - pathology; Humans; Infant; Male; Menkes Kinky Hair Syndrome - metabolism; Menkes Kinky Hair Syndrome - pathology; Metallothionein - metabolism; Skin - cytology; Skin - metabolism

Copper concentration, intracellular copper distribution, and inducibility of metallothionein-like metal-binding protein (MLP) by copper or cadmium addition to culture medium were compared among three types of skin fibroblasts derived from patients with Menkes' disease and Wilson's disease,...