Stromelysin-1 (MMP-3) level in the sera from patients with rheumatoid arthritis and other connective tissue diseases--clinical significances in early onset rheumatoid arthritis

• Published in: Ryumachi. [Rheumatism] Vol. 35; no. 1; p. 15
• Main Authors: Shingu, M, Obata, K, Ezaki, I, Tomari, K, Fujikawa, Y, Wada, T, Nonaka, S, Suenaga, Y, Iwata, K, Nobunaga, M
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.02.1995
• Subjects: Aged; Arthritis, Rheumatoid - diagnosis; Biomarkers - blood; Connective Tissue Diseases - diagnosis; Female; Humans; Immunoenzyme Techniques; Male; Matrix Metalloproteinase 3; Metalloendopeptidases - blood; Middle Aged

Stromelysin-1 (MMP-3) is a metalloproteinase that degrades articular cartilage matrix in patients with rheumatoid arthritis (RA). We measured MMP-3 in the sera from patients with RA and other connective tissue diseases using specific sandwich EIA and studied its clinical significance in early onset...