Qualitative and quantitative evaluation of CFU-E colonies in myelodysplastic syndromes

• Published in: Rinsho byori. The Japanese journal of clinical pathology Vol. 39; no. 12; p. 1342
• Main Authors: Maruo, N, Ozawa, M, Kimura, S, Kondo, M, Fujita, S, Fukuda, M
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.12.1991
• Subjects: Adult; Aged; Bone Marrow - pathology; Colony-Forming Units Assay; Erythroid Precursor Cells - pathology; Female; Humans; Male; Myelodysplastic Syndromes - pathology

Hemoglobin (Hb) synthesis in colony-forming-unit erythroid (CFU-E) colonies from the bone marrow of 10 normal subjects and 6 patients with myelodysplastic syndromes (MDS) was studied using microcytofluorometry. Hb content was determined utilizing a photochemical reaction in which the intracellular H...