Some problems of the criteria for response evaluation of cancer chemotherapy of the digestive organs

• Published in: Gan to kagaku ryoho Vol. 16; no. 3 Pt 1; p. 302
• Main Author: Nakao, I
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.03.1989
• Subjects: Antineoplastic Agents - therapeutic use; Clinical Trials as Topic; Esophageal Neoplasms - drug therapy; Humans; Prognosis; Stomach Neoplasms - drug therapy
• ISSN: 0385-0684

The criteria for response evaluation of cancer chemotherapy of digestive organs were discussed on the clinical application of stomach and esophagus cancer which the criteria are almost established. The responses of primary site are evaluated on the changes of tumor size by imaging diagnosis, and the uniformity and objectivity of response representation due to the sort of lesion cause the problems, so for studies are carrying out in many cases. Furthermore, response rate, survival time and quality of life were discussed in relation to clinical studies how to manage it at present and the problems in future referred. The criteria for response evaluation is a rule and interpreted different senses due to the objects of clinical studies. According to accumulate the clinical studies with exact significances and objects, various problems will be solved.