Preliminary results with an oral application of killed Purtussis bacteria in newborn infants

• Published in: Developments in biological standardization Vol. 33; p. 54
• Main Authors: Stickl, H, Schweier, P, van Thiel, D
• Format: Journal Article
• Language: English
• Published: Switzerland 1976
• Subjects: Administration, Oral; Antibodies, Bacterial - analysis; Antibody Formation; Bordetella pertussis - immunology; Humans; Infant, Newborn; Pertussis Vaccine - administration & dosage; Pertussis Vaccine - therapeutic use; Whooping Cough - prevention & control

Newborn babies have been vaccinated orally on five consecutive days, with 5 droplets of a vaccine containing 10(11) killed Bordetella pertussis. Eight out of twelve subjects showed antibody titres varying between 1:20 and 1:80.