Stereoselective Synthesis of (Sulfonimidoyl)cyclopropanes with (R)-PhSO(NTs)CH2Cl and ,-Unsaturated Weinreb Amides: Tuning the of Selectivity between C-Cl and C-S Bond Cleavage

• Published in: European journal of organic chemistry Vol. 2016; no. 5; pp. 906 - 909
• Main Authors: Shen, Xiao, Liu, Qinghe, Zhang, Wei, Hu, Jinbo
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 01.02.2016; Wiley Subscription Services, Inc
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; ORGANIC-SYNTHESIS; SUBSTITUTION; SULFOXIMINES; CYCLOPROPANES; C-Cl bond cleavage; ALPHA-FLUOROSULFOXIMINES; Cyclopropanation; C-S bond cleavage; Cyclopropane; Sulfoximine; MONOFLUOROALKENES; ARYL KETONES; NUCLEOPHILIC DIFLUOROMETHYLATION; DERIVATIVES; PHSO(NTBS)CF2H

(Sulfonimidoyl)cyclopropanes have become the subject of special interest since they combine the advantages of two chemical leads (cyclopropane and sulfoximine). However, their synthesis is limited, and the stereoselective synthesis of optically enriched (sulfonimidoyl)cyclopropanes still remains an...