Cytochrome P450 and Epoxide Hydrolase Metabolites in Aβ and tau-induced Neurodegeneration: Insights from Caenorhabditis elegans

This study aims to uncover potent cytochrome P450 (CYP) and epoxide hydrolase (EH) metabolites implicated in Aβ and/or tau-induced neurodegeneration, independent of neuroinflammation, by utilizing ( ) as a model organism. Our research reveals that Aβ and/or tau expression in disrupts the oxylipin pr...

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Bibliographic Details
Published inbioRxiv : the preprint server for biology
Main Authors Sarparast, Morteza, Hinman, Jennifer, Pourmand, Elham, Vonarx, Derek, Ramirez, Leslie, Ma, Wenjuan, Liachko, Nicole F, Alan, Jamie K, Lee, Kin Sing Stephen
Format Journal Article
LanguageEnglish
Published United States 02.10.2023
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