The role of the marrow microenvironment in hematopoietic stem cell transplantation

• Published in: Cellular therapy and transplantation Vol. 2; no. 7; pp. 7 - 12
• Main Authors: Ramakrishnan, Aravind, Torok-Storb, Beverly J
• Format: Journal Article
• Language: English
• Published: Germany 01.04.2010

The success of hematopoietic stem cell transplantation depends on the engraftment of pluripotent hematopoietic stem cells and the regulated proliferation and maturation of committed progenitor cells. It is generally agreed that these processes cannot occur without an appropriate milieu provided by a...