6',7'-Dimeth-oxy-1',2'-dihydro-spiro-[cyclo-hexane-1,2'-quinazolin]-4'(3'H)-one
In the title compound, C(15)H(20)N(2)O(3), prepared from the reaction of 2-amino-4,5-dimeth-oxy-benzonitrile and cyclo-hexa-none, the six-membered diaza ring assumes an envelope conformation. In the crystal, inversion dimers are formed by pairs of N-H⋯O hydrogen bonds. Futher N-H⋯O hydrogen bonds li...
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| Published in | Acta crystallographica. Section E, Structure reports online Vol. 67; no. Pt 12; p. o3389 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
International Union of Crystallography
01.12.2011
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| Subjects | |
| Online Access | Get full text |
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| Abstract | In the title compound, C(15)H(20)N(2)O(3), prepared from the reaction of 2-amino-4,5-dimeth-oxy-benzonitrile and cyclo-hexa-none, the six-membered diaza ring assumes an envelope conformation. In the crystal, inversion dimers are formed by pairs of N-H⋯O hydrogen bonds. Futher N-H⋯O hydrogen bonds link the dimers into a two-dimensional structure parallel to (001). |
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| AbstractList | In the title compound, C
15
H
20
N
2
O
3
, prepared from the reaction of 2-amino-4,5-dimethoxybenzonitrile and cyclohexanone, the six-membered diaza ring assumes an envelope conformation. In the crystal, inversion dimers are formed by pairs of N—H⋯O hydrogen bonds. Futher N—H⋯O hydrogen bonds link the dimers into a two-dimensional structure parallel to (001). In the title compound, C(15)H(20)N(2)O(3), prepared from the reaction of 2-amino-4,5-dimeth-oxy-benzonitrile and cyclo-hexa-none, the six-membered diaza ring assumes an envelope conformation. In the crystal, inversion dimers are formed by pairs of N-H⋯O hydrogen bonds. Futher N-H⋯O hydrogen bonds link the dimers into a two-dimensional structure parallel to (001). |
| Author | Zhang, Li-Jun Li, Hui Luo, Xiang-Ning Song, Yang |
| Author_xml | – sequence: 1 givenname: Li-Jun surname: Zhang fullname: Zhang, Li-Jun organization: School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin 300384, People's Republic of China – sequence: 2 givenname: Yang surname: Song fullname: Song, Yang – sequence: 3 givenname: Xiang-Ning surname: Luo fullname: Luo, Xiang-Ning – sequence: 4 givenname: Hui surname: Li fullname: Li, Hui |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22199878$$D View this record in MEDLINE/PubMed |
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| Copyright | Zhang et al. 2011 2011 |
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| References | 21201476 - Acta Crystallogr Sect E Struct Rep Online. 2008;64(Pt 2):o449 17256924 - J Med Chem. 2007 Feb 22;50(4):663-73 11087572 - J Med Chem. 2000 Nov 16;43(23):4479-87 18156677 - Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22 |
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| Snippet | In the title compound, C(15)H(20)N(2)O(3), prepared from the reaction of 2-amino-4,5-dimeth-oxy-benzonitrile and cyclo-hexa-none, the six-membered diaza ring... In the title compound, C 15 H 20 N 2 O 3 , prepared from the reaction of 2-amino-4,5-dimethoxybenzonitrile and cyclohexanone, the six-membered diaza ring... |
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| Title | 6',7'-Dimeth-oxy-1',2'-dihydro-spiro-[cyclo-hexane-1,2'-quinazolin]-4'(3'H)-one |
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