Spectral clustering as a diagnostic tool in cross-sectional MR studies: an application to mild dementia

• Published in: Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention Vol. 11; no. Pt 2; p. 442
• Main Authors: Aljabar, Paul, Rueckert, Daniel, Crum, William R
• Format: Journal Article
• Language: English
• Published: Germany 2008
• Subjects: Aged; Algorithms; Artificial Intelligence; Brain - pathology; Cluster Analysis; Cross-Sectional Studies; Dementia - diagnosis; Female; Humans; Image Enhancement - methods; Image Interpretation, Computer-Assisted - methods; Imaging, Three-Dimensional - methods; Magnetic Resonance Imaging - methods; Male; Pattern Recognition, Automated - methods; Reproducibility of Results; Sensitivity and Specificity; Subtraction Technique

Structural imaging investigations commonly apply a segmentation step followed by the extraction of feature data that can be used to compare or discriminate groups. We present a framework for such a study based on automated multi-atlas segmentation followed by the extraction of low-level morphologica...