Assessment of the antinociceptive, respiratory-depressant, and reinforcing effects of the low pK a fluorinated fentanyl analogs, FF3 and NFEPP - Edwards, Shelley R; Blough, Bruce E; Cowart, Kristian; Howell, Grace H; Araujo, Aaron A; Haskell, Jacob P; Huskinson, Sally L; Rowlett, James K; Brackeen, Marcus F; Freeman, Kevin B (Neuropharmacology, 2024)
Keywords: Analgesics, Opioid - pharmacology; Animals; Dose-Response Relationship, Drug; Female; Fentanyl - analogs & derivatives; Fentanyl - pharmacology; Male; Pain Measurement - drug effects; Pain Measurement - methods; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Respiratory Insufficiency - chemically induced; Self Administration; Fentanyl; Fentanyl analogs; Self-administration; Antinociception; Respiratory depression; pKa