Reprogramming patient-iPSC specific retinal organoids for deciphering epigenetic modifications of RNA methylation

• Published in: Journal of the Chinese Medical Association
• Main Authors: Chien, Yueh, Yang, Yi-Ping, Lin, Tai-Chi, Chiou, Guang-Yuh, Yarmishyn, Aliaksandr A, Wang, Chia-Hao, Ching, Lo-Jei, Lin, Yi-Ying, Chen, Shih-Jen, Hwang, De-Kuang, Hsu, Chih-Chien
• Format: Journal Article
• Language: English
• Published: 23.12.2024

Induced pluripotent stem cell (iPSC) technology has emerged as a powerful tool for disease modeling, providing an innovative platform for investigating disease mechanisms. iPSC-derived organoids, including retinal organoids, offer patient-specific models that closely replicate in vivo cellular envir...