Immunomodulating potential of supplementation with probiotics: a dose-response study in healthy young adults

• Published in: FEMS immunology and medical microbiology Vol. 47; no. 3; pp. 380 - 390
• Main Authors: Christensen, Hanne Risager, Larsen, Charlotte Nexmann, Kæstel, Pernille, Rosholm, Lisbeth Buus, Sternberg, Claus, Michaelsen, Kim Fleischer, Frøkiær, Hanne
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.08.2006; Oxford University Press
• Subjects: Adolescent; Adult; Adults; Bifidobacterium - immunology; Bifidobacterium - isolation & purification; Cytokines - blood; Dietary Supplements; Dose-Response Relationship, Immunologic; dose–response; Double-Blind Method; Feces - microbiology; Female; healthy human adults; Humans; Immune response; Immunoglobulin A; Immunoglobulin A - analysis; Immunoglobulin A - blood; Immunoglobulins - blood; Immunologic Factors - administration & dosage; immunomodulation; Interferon; Interleukin 10; Lactobacillus - immunology; Lactobacillus - isolation & purification; Lactobacillus paracasei; Leukocytes; Lymphocyte Activation; Male; Microorganisms; Phagocytes; Phagocytes - drug effects; Phagocytosis; probiotic; Probiotics; Probiotics - administration & dosage; Statistical analysis; Supplements; Young adults; γ-Interferon; immunomodulation; probiotic; dose—response; healthy human adults

Abstract Certain probiotic microorganisms have been found beneficial in the treatment of immune-related diseases and may also affect immune function in healthy people. Intervention studies of probiotics in healthy humans are urgently required. Here, the immunomodulating potential of Bifidobacterium...