The Ins and Outs of miRNAs as Biomarkers

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: AECII; alveolar epithelial type II cells; amniotic fluid; amplification efficiency; angiogenesis; ATII; autofluorescence; Biology, life sciences; breast cancer; cancer biomarkers; cervical cancer; chemoresistance; chemosensitivity; children/adolescents; chronic low-grade inflammation; circulating microRNAs; circulating miRNA; comparative study; diagnosis; diagnostics; divergent cell commitment; DNA copy number variation; down-regulation; EBV; EMT; expression profiling; extracellular miRNA; flow cytometry; FOXD1; gene expression; hazard ratio; HCV genotype-3; head and neck cancer; hepatitis C virus; HNSCC; homeostasis; inflammation-associated biomarkers; leiomyoma; linear dysregulation; liver injury; liver neoplasms; LMP1; Mathematics and Science; melanoma; meta-analysis; mi-RNA; microRNA; microRNA-192; microRNA-29a; microRNAs; miR-30e-5p; miRNA; miRNA-based diagnosis; miRNAs; myometrium; nasopharyngeal carcinoma; nasopharyngeal cells; non-coding RNAs; overweight and obesity; pathway analysis; patient survival; personalized medicine; physical exercise; plasma; progenitor cells; prognosis; protocol; qRT-PCR; Reference, Information and Interdisciplinary subjects; regulation of gene expression; Research and information: general; RNA-based therapeutic; sex-related associations; stress; systematic review; TCGA; TGF-beta; theranostic biomarkers; therapeutics; therapy response; transfection; translational medicine; tumor-suppressor; type II pneumocytes; up-regulation

miRNAs are small noncoding RNAs that control gene expression at the post-transcriptional level. It has been recognized that dysregulation of miRNAs reflects the state and function of cells and tissues, contributing to their dysfunction. The identification of hundreds of extracellular miRNAs in biolo...