Stem Cells and Irradiation

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: acute respiratory-distress syndrome; adipose tissue derived stem cells; ALDH activity; annexin A1; BCSC; Biology, life sciences; cancer-stem like cells; cell technologies; cell therapy; colorectal cancer; conditioned medium; COVID-19; dysplasia; epithelial-to-mesenchymal transition (EMT); epithelial–mesenchymal transition (EMT); exosome; experimental radiotherapy; extracellular vesicles; fibrosis; fractionated dose of γ radiation; human epidermis; Keap1; keratinocytes; local radiation injuries; low-dose γ irradiation; macrophages; Mathematics and Science; mesenchymal; mesenchymal stem cell; mesenchymal stem cells; micro vesicles; miR200a; n/a; Nrf2; organoids; paracrine effect; PI3K/AKT; placenta; precursor cells; Radiation; radiation cystitis; radiation damage; radiation therapy; radiation-induced injury; radiobiology; radioresistance; radiotherapy; Reference, Information and Interdisciplinary subjects; regeneration; Research and information: general; ROS; skin; SOX2; stem cell; stem cells; stem cells therapy; stem/progenitor cells; treatment; X-ray radiation; ZEB1

The main difficulty of radiotherapy is to destroy cancer cells without depletion of healthy tissue. Stem cells and cancers are tightly interrelated. On one hand, radiosensitivity/radioressistance of cancer stem cells affects the radiocurability of tumors. On the other hand, radiosensitivity is respo...