Kaempferol Downregulates Insulin-like Growth Factor-I Receptor and ErbB3 Signaling in HT-29 Human Colon Cancer Cells

• Published in: Journal of cancer prevention Vol. 19; no. 3; pp. 161 - 169
• Main Authors: Lee, Hyun Sook, Cho, Han Jin, Kwon, Gyoo Taik, Park, Jung Han Yoon
• Format: Journal Article
• Language: English
• Published: Korea (South) 대한암예방학회 01.09.2014
• Subjects: 예방의학; Insulin-like growth factor-I receptor; HT-29 human colon cancer; Kaempferol; ErbB3

Novel dietary agents for colon cancer prevention and therapy are desired. Kaempferol, a flavonol, has been reported to possess anticancer activity. However, little is known about the molecular mechanisms of the anticancer effects of kaempferol. The aim of this study was to determine the inhibitory e...