Heart functions in monkeys during a 2-week antiorthostatic hypokinesia

Dynamics of the left heart ventricular muscle contractility and compliance was studied in 4 monkeys in the head down position (antiorthostatic hypokinesia) with the body angle 10 during 2 weeks. Functional tests on a tilt table and under two conditions of centrifuge rotation were performed prior to...

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Bibliographic Details
Published inFiziologicheskii zhurnal imeni I.M. Sechenova Vol. 82; no. 10-11; p. 34
Main Authors Krotov, V P, Convertino, V, Korol'kov, V I, Latham, R, Trambovetskiĭ, E V, Fanton, J, Crisman, R, Truzhennikov, A N, Evert, D, Nosovskiĭ, A M, Conolly, J
Format Journal Article
LanguageEnglish
Russian
Published Russia (Federation) 01.10.1996
Subjects
Animals
Centrifugation
Electrocardiography - methods
Head-Down Tilt - physiology
Heart - physiopathology
Hemodynamics
Hypokinesia - physiopathology
Macaca mulatta
Myocardial Contraction - physiology
Thermodilution - methods
Time Factors
NASA Discipline Regulatory Physiology
Non-NASA Center
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Summary:Dynamics of the left heart ventricular muscle contractility and compliance was studied in 4 monkeys in the head down position (antiorthostatic hypokinesia) with the body angle 10 during 2 weeks. Functional tests on a tilt table and under two conditions of centrifuge rotation were performed prior to and after the antiorthostatic hypokinesia. No changes in the left heart ventricular muscle contractility was found. However, the sensitivity level of the baroreflex control decreased. Compliance of the left heart myocardial fibre increased in the first hours and days of the antiorthostatic hypokinesia.
ISSN:1027-3646