하지 근육형동맥과 복부 탄력형동맥의 동맥경화위험요소의 비교

• Published in: Annals of surgical treatment and research Vol. 79; no. 6; pp. 481 - 485
• Main Authors: 박종권(Jong Kwon Park), 김관우(Kwan Woo Kim), 박정익(Jeong-Ik Park), 오성진(Sung Jin Oh), 서병조(Byoung Jo Suh), 오상훈(Sang Hoon Oh), 전시열(Si-Youl Jun)
• Format: Journal Article
• Language: Korean
• Published: 대한외과학회 01.12.2010
• Subjects: 일반외과학; Hypertension; 탄력형동맥; Muscular artery; 맥파전파속도; Elastic artery; Pulse wave velocity; 근육형동맥; 고혈압
• ISSN: 2288-6575; 2288-6796

Purpose: Muscular artery differs from elastic artery in physical properties and constituents of the arterial wall. To investigate the difference between muscular and elastic arteries, we measured the pulse wave velocities (PWVs) in lower extremity muscular arteries (femoral ankle PWV, faPWV) and abdominal elastic arteries (brachial femoral PWV, bfPWV), and searched for the relationships between the PWVs of muscular, elastic arteries and the risk factors of arteriosclerosis. Methods: 184 normal volunteers were enrolled in the study. Among them, the ratios of male/female, smoker/ non-smoker, and hypertension/normal were 81/103, 66/118, and 63/121, respectively. Using volume plethysmography, faPWV and bfPWV were measured. The risk factors of arteriosclerosis in this study were age, gender, smoking, hypertension, body mass index, low density lipoprotein, high density lipoprotein, triglyceride, hemoglobin A1C, and white blood cell. Results: The PWVs of lower extremity muscular arteries (faPWVs) were significantly faster than those of abdominal elastic arteries (bfPWVs) (right, P＜0.001; left, P＜0.001) Multiple regression analysis revealed that the independent risk factors of the PWV were age (right, P＜0.001; left, P＜0.001) and gender (right, P=0.008; left, p=0.014) in abdominal elastic arteries. However, in lower extremity muscular arteries, hypertension (right, P＜0.001; left, P＜0.001) as well as age (right, P＜0.001; left, P＜0.001) and gender (right, P=0.009; left, P=0.001) were other significant independent risk factors. Conclusion: The PWVs of lower extremity muscular arteries were significantly faster than those of abdominal elastic arteries. The significance of hypertension in faPWV suggests that hypertension is an important risk factor in inducing arterial stiffness, especially in lower extremity muscular arteries. KCI Citation Count: 0