Detection of recurrence by 18F-FDG PET in patients with endometrial cancer showing no evidence of disease
This study assessed the feasibility of F-18-fluorodeoxyglucose positron-emission tomography ((18)F-FDG PET) in the post-therapy surveillance for patients with endometrial cancer showing no evidence of disease (NED). From April 1997 to June 2007, 127 patients with endometrial cancer showing NED were...
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Published in | Journal of Korean medical science Vol. 25; no. 7; pp. 1029 - 1033 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Korea (South)
The Korean Academy of Medical Sciences
01.07.2010
대한의학회 |
Subjects | |
Online Access | Get full text |
ISSN | 1598-6357 1011-8934 1598-6357 |
DOI | 10.3346/jkms.2010.25.7.1029 |
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Abstract | This study assessed the feasibility of F-18-fluorodeoxyglucose positron-emission tomography ((18)F-FDG PET) in the post-therapy surveillance for patients with endometrial cancer showing no evidence of disease (NED). From April 1997 to June 2007, 127 patients with endometrial cancer showing NED were performed (18)F-FDG PET scan. The feasibility of (18)F-FDG PET for the early detection of recurrence in patients with endometrial cancer was evaluated retrospectively. Of the 127 patients, 32 patients showed positive lesions on (18)F-FDG PET scan. Nineteen (19/127 cases, 15%) of them were confirmed to have a recurrence clinically or histologically. The sensitivity, specificity and positive and negative predictive value of (18)F-FDG PET for detecting recurrences in patients with endometrial cancer were 100%, 88%, 59% and 100%, respectively. In conclusion, (18)F-FDG PET may be a useful method for the post-therapy surveillance in patients with endometrial cancer. |
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AbstractList | This study assessed the feasibility of F-18-fluorodeoxyglucose positron-emission tomography ((18)F-FDG PET) in the post-therapy surveillance for patients with endometrial cancer showing no evidence of disease (NED). From April 1997 to June 2007, 127 patients with endometrial cancer showing NED were performed (18)F-FDG PET scan. The feasibility of (18)F-FDG PET for the early detection of recurrence in patients with endometrial cancer was evaluated retrospectively. Of the 127 patients, 32 patients showed positive lesions on (18)F-FDG PET scan. Nineteen (19/127 cases, 15%) of them were confirmed to have a recurrence clinically or histologically. The sensitivity, specificity and positive and negative predictive value of (18)F-FDG PET for detecting recurrences in patients with endometrial cancer were 100%, 88%, 59% and 100%, respectively. In conclusion, (18)F-FDG PET may be a useful method for the post-therapy surveillance in patients with endometrial cancer. This study assessed the feasibility of F-18-fluorodeoxyglucose positron-emission tomography ( 18 F-FDG PET) in the post-therapy surveillance for patients with endometrial cancer showing no evidence of disease (NED). From April 1997 to June 2007, 127 patients with endometrial cancer showing NED were performed 18 F-FDG PET scan. The feasibility of 18 F-FDG PET for the early detection of recurrence in patients with endometrial cancer was evaluated retrospectively. Of the 127 patients, 32 patients showed positive lesions on 18 F-FDG PET scan. Nineteen (19/127 cases, 15%) of them were confirmed to have a recurrence clinically or histologically. The sensitivity, specificity and positive and negative predictive value of 18 F-FDG PET for detecting recurrences in patients with endometrial cancer were 100%, 88%, 59% and 100%, respectively. In conclusion, 18 F-FDG PET may be a useful method for the post-therapy surveillance in patients with endometrial cancer. This study assessed the feasibility of F-18-fluorodeoxyglucose positron-emission tomography (18F-FDG PET) in the post-therapy surveillance for patients with endometrial cancer showing no evidence of disease (NED). From April 1997 to June 2007, 127 patients with endometrial cancer showing NED were performed 18F-FDG PET scan. The feasibility of 18F-FDG PET for the early detection of recurrence in patients with endometrial cancer was evaluated retrospectively. Of the 127 patients, 32 patients showed positive lesions on 18F-FDG PET scan. Nineteen (19/127 cases, 15%) of them were confirmed to have a recurrence clinically or histologically. The sensitivity, specificity and positive and negative predictive value of 18F-FDG PET for detecting recurrences in patients with endometrial cancer were 100%, 88%, 59% and 100%, respectively. In conclusion, 18F-FDG PET may be a useful method for the post-therapy surveillance in patients with endometrial cancer. KCI Citation Count: 3 This study assessed the feasibility of F-18-fluorodeoxyglucose positron-emission tomography ((18)F-FDG PET) in the post-therapy surveillance for patients with endometrial cancer showing no evidence of disease (NED). From April 1997 to June 2007, 127 patients with endometrial cancer showing NED were performed (18)F-FDG PET scan. The feasibility of (18)F-FDG PET for the early detection of recurrence in patients with endometrial cancer was evaluated retrospectively. Of the 127 patients, 32 patients showed positive lesions on (18)F-FDG PET scan. Nineteen (19/127 cases, 15%) of them were confirmed to have a recurrence clinically or histologically. The sensitivity, specificity and positive and negative predictive value of (18)F-FDG PET for detecting recurrences in patients with endometrial cancer were 100%, 88%, 59% and 100%, respectively. In conclusion, (18)F-FDG PET may be a useful method for the post-therapy surveillance in patients with endometrial cancer.This study assessed the feasibility of F-18-fluorodeoxyglucose positron-emission tomography ((18)F-FDG PET) in the post-therapy surveillance for patients with endometrial cancer showing no evidence of disease (NED). From April 1997 to June 2007, 127 patients with endometrial cancer showing NED were performed (18)F-FDG PET scan. The feasibility of (18)F-FDG PET for the early detection of recurrence in patients with endometrial cancer was evaluated retrospectively. Of the 127 patients, 32 patients showed positive lesions on (18)F-FDG PET scan. Nineteen (19/127 cases, 15%) of them were confirmed to have a recurrence clinically or histologically. The sensitivity, specificity and positive and negative predictive value of (18)F-FDG PET for detecting recurrences in patients with endometrial cancer were 100%, 88%, 59% and 100%, respectively. In conclusion, (18)F-FDG PET may be a useful method for the post-therapy surveillance in patients with endometrial cancer. |
Author | Lee, Eui-Don Kim, Kidong Ryu, Sang-Young Park, Sang-Il Kim, Younha Kim, Moon-Hong Kim, Beob-Jong Lee, Kyung-Hee Kim, Byung Il Choi, Seok-Cheol |
AuthorAffiliation | 1 Department of Obstetrics & Gynecology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, Korea 2 Department of Nuclear Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, Korea |
AuthorAffiliation_xml | – name: 2 Department of Nuclear Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, Korea – name: 1 Department of Obstetrics & Gynecology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, Korea |
Author_xml | – sequence: 1 givenname: Sang-Young surname: Ryu fullname: Ryu, Sang-Young email: ryu@kcch.re.kr organization: Department of Obstetrics & Gynecology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Korea. ryu@kcch.re.kr – sequence: 2 givenname: Kidong surname: Kim fullname: Kim, Kidong – sequence: 3 givenname: Younha surname: Kim fullname: Kim, Younha – sequence: 4 givenname: Sang-Il surname: Park fullname: Park, Sang-Il – sequence: 5 givenname: Beob-Jong surname: Kim fullname: Kim, Beob-Jong – sequence: 6 givenname: Moon-Hong surname: Kim fullname: Kim, Moon-Hong – sequence: 7 givenname: Seok-Cheol surname: Choi fullname: Choi, Seok-Cheol – sequence: 8 givenname: Eui-Don surname: Lee fullname: Lee, Eui-Don – sequence: 9 givenname: Kyung-Hee surname: Lee fullname: Lee, Kyung-Hee – sequence: 10 givenname: Byung Il surname: Kim fullname: Kim, Byung Il |
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Keywords | Recurrence Positron-Emission Tomography Endometrial Neoplasms |
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SubjectTerms | Adult Aged Endometrial Neoplasms - diagnosis Endometrial Neoplasms - diagnostic imaging Endometrial Neoplasms - pathology Female Fluorodeoxyglucose F18 Humans Middle Aged Neoplasm Recurrence, Local - diagnosis Neoplasm Recurrence, Local - diagnostic imaging Neoplasm Recurrence, Local - pathology Original Positron-Emission Tomography - methods Predictive Value of Tests Retrospective Studies Sensitivity and Specificity 의학일반 |
Title | Detection of recurrence by 18F-FDG PET in patients with endometrial cancer showing no evidence of disease |
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