Supplementating with dietary astaxanthin combined with collagen hydrolysate improves facial elasticity and decreases matrix metalloproteinase-1 and -12 expression: a comparative study with placebo

• Published in: Journal of medicinal food Vol. 17; no. 7; p. 810
• Main Authors: Yoon, Hyun-Sun, Cho, Hyun Hee, Cho, Soyun, Lee, Se-Rah, Shin, Mi-Hee, Chung, Jin Ho
• Format: Journal Article
• Language: English
• Published: United States 01.07.2014
• Subjects: Adult; Antioxidants - administration & dosage; Asian Continental Ancestry Group; Collagen - administration & dosage; Collagen Type I - genetics; Collagen Type I - metabolism; Dietary Supplements; DNA Damage - drug effects; DNA Damage - radiation effects; Double-Blind Method; Elasticity; Female; Fibrillin-1; Fibrillins; Humans; Matrix Metalloproteinase 1 - genetics; Matrix Metalloproteinase 1 - metabolism; Matrix Metalloproteinase 12 - genetics; Matrix Metalloproteinase 12 - metabolism; Microfilament Proteins - genetics; Microfilament Proteins - metabolism; Middle Aged; Patient Compliance; RNA, Messenger - genetics; RNA, Messenger - metabolism; Skin - drug effects; Skin - metabolism; Skin Aging - drug effects; Ultraviolet Rays - adverse effects; Xanthophylls - administration & dosage; anti-aging; astaxanthin; collagen hydrolysate; photoaging

Photoaging accounts for most age-related changes in skin appearance. It has been suggested that both astaxanthin, a potent antioxidant, and collagen hydrolysate can be used as antiaging modalities in photoaged skin. However, there is no clinical study using astaxanthin combined with collagen hydroly...