The latest techniques for inducing macrophage differentiation
Macrophages play a prominent role in tissue development, homeostasis, and repair. In addition, their fundamental and well-known functions are integral to the host’s defense system, including immune responses and debris removal from apoptotic cells. These immune cells are remarkably responsive to var...
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Published in | Biotechnology and bioprocess engineering Vol. 29; no. 3; pp. 440 - 450 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Seoul
The Korean Society for Biotechnology and Bioengineering
01.06.2024
Springer Nature B.V 한국생물공학회 |
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Abstract | Macrophages play a prominent role in tissue development, homeostasis, and repair. In addition, their fundamental and well-known functions are integral to the host’s defense system, including immune responses and debris removal from apoptotic cells. These immune cells are remarkably responsive to various stimuli in the microenvironment, inducing multiple forms of differentiation with distinct phenotypes and roles. These stimuli comprise biochemical signals and physical biomaterial properties. Thus, understanding how immune cells differentiate is crucial for designing biomaterials, tissue scaffolds, implantable materials, and regenerative medicine, such as developing new drugs and immunomodulatory drug delivery systems. This review discusses about the latest techniques in inducing immune cell differentiation. |
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AbstractList | Macrophages play a prominent role in tissue development, homeostasis, and repair. In addition, their fundamental and well-known functions are integral to the host’s defense system, including immune responses and debris removal from apoptotic cells. These immune cells are remarkably responsive to various stimuli in the microenvironment, inducing multiple forms of differentiation with distinct phenotypes and roles. These stimuli comprise biochemical signals and physical biomaterial properties. Thus, understanding how immune cells differentiate is crucial for designing biomaterials, tissue scaffolds, implantable materials, and regenerative medicine, such as developing new drugs and immunomodulatory drug delivery systems. This review discusses about the latest techniques in inducing immune cell differentiation. Macrophages play a prominent role in tissue development, homeostasis, and repair. In addition, their fundamental and wellknown functions are integral to the host’s defense system, including immune responses and debris removal from apoptotic cells. These immune cells are remarkably responsive to various stimuli in the microenvironment, inducing multiple forms of diff erentiation with distinct phenotypes and roles. These stimuli comprise biochemical signals and physical biomaterial properties. Thus, understanding how immune cells diff erentiate is crucial for designing biomaterials, tissue scaff olds, implantable materials, and regenerative medicine, such as developing new drugs and immunomodulatory drug delivery systems. This review discusses about the latest techniques in inducing immune cell diff erentiation. KCI Citation Count: 0 |
Author | Choi, Yonghyun Kim, Namju Lee, Kyungwoo Choi, Jonghoon Lee, Hee-Young |
Author_xml | – sequence: 1 givenname: Kyungwoo surname: Lee fullname: Lee, Kyungwoo organization: School of Integrative Engineering, Chung-Ang University – sequence: 2 givenname: Yonghyun surname: Choi fullname: Choi, Yonghyun organization: School of Integrative Engineering, Chung-Ang University, Feynman Institute of Technology, Nanomedicine Corporation, Department of Chemical Science and Engineering, Tokyo Institute of Technology – sequence: 3 givenname: Namju surname: Kim fullname: Kim, Namju organization: School of Integrative Engineering, Chung-Ang University – sequence: 4 givenname: Hee-Young surname: Lee fullname: Lee, Hee-Young email: lhysshr@kumoh.ac.kr organization: Department of Chemical Engineering, Kumoh National Institute of Technology – sequence: 5 givenname: Jonghoon orcidid: 0000-0003-3554-7033 surname: Choi fullname: Choi, Jonghoon email: nanomed@cau.ac.kr organization: School of Integrative Engineering, Chung-Ang University, Feynman Institute of Technology, Nanomedicine Corporation |
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