The latest techniques for inducing macrophage differentiation

Macrophages play a prominent role in tissue development, homeostasis, and repair. In addition, their fundamental and well-known functions are integral to the host’s defense system, including immune responses and debris removal from apoptotic cells. These immune cells are remarkably responsive to var...

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Published inBiotechnology and bioprocess engineering Vol. 29; no. 3; pp. 440 - 450
Main Authors Lee, Kyungwoo, Choi, Yonghyun, Kim, Namju, Lee, Hee-Young, Choi, Jonghoon
Format Journal Article
LanguageEnglish
Published Seoul The Korean Society for Biotechnology and Bioengineering 01.06.2024
Springer Nature B.V
한국생물공학회
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Abstract Macrophages play a prominent role in tissue development, homeostasis, and repair. In addition, their fundamental and well-known functions are integral to the host’s defense system, including immune responses and debris removal from apoptotic cells. These immune cells are remarkably responsive to various stimuli in the microenvironment, inducing multiple forms of differentiation with distinct phenotypes and roles. These stimuli comprise biochemical signals and physical biomaterial properties. Thus, understanding how immune cells differentiate is crucial for designing biomaterials, tissue scaffolds, implantable materials, and regenerative medicine, such as developing new drugs and immunomodulatory drug delivery systems. This review discusses about the latest techniques in inducing immune cell differentiation.
AbstractList Macrophages play a prominent role in tissue development, homeostasis, and repair. In addition, their fundamental and well-known functions are integral to the host’s defense system, including immune responses and debris removal from apoptotic cells. These immune cells are remarkably responsive to various stimuli in the microenvironment, inducing multiple forms of differentiation with distinct phenotypes and roles. These stimuli comprise biochemical signals and physical biomaterial properties. Thus, understanding how immune cells differentiate is crucial for designing biomaterials, tissue scaffolds, implantable materials, and regenerative medicine, such as developing new drugs and immunomodulatory drug delivery systems. This review discusses about the latest techniques in inducing immune cell differentiation.
Macrophages play a prominent role in tissue development, homeostasis, and repair. In addition, their fundamental and wellknown functions are integral to the host’s defense system, including immune responses and debris removal from apoptotic cells. These immune cells are remarkably responsive to various stimuli in the microenvironment, inducing multiple forms of diff erentiation with distinct phenotypes and roles. These stimuli comprise biochemical signals and physical biomaterial properties. Thus, understanding how immune cells diff erentiate is crucial for designing biomaterials, tissue scaff olds, implantable materials, and regenerative medicine, such as developing new drugs and immunomodulatory drug delivery systems. This review discusses about the latest techniques in inducing immune cell diff erentiation. KCI Citation Count: 0
Author Choi, Yonghyun
Kim, Namju
Lee, Kyungwoo
Choi, Jonghoon
Lee, Hee-Young
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Snippet Macrophages play a prominent role in tissue development, homeostasis, and repair. In addition, their fundamental and well-known functions are integral to the...
Macrophages play a prominent role in tissue development, homeostasis, and repair. In addition, their fundamental and wellknown functions are integral to the...
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SubjectTerms Antigens
Apoptosis
biocompatible materials
Biomaterials
Biomedical materials
Biotechnology
Bone marrow
Cell differentiation
Chemistry
Chemistry and Materials Science
Cytokines
Differentiation (biology)
Drug delivery
Drug delivery systems
drugs
Foreign bodies
Homeostasis
Immune response
Immune system
Immunomodulation
Immunosuppressive agents
Industrial and Production Engineering
Infections
Inflammation
Macrophages
medicine
Microenvironments
Pathogens
Phenotypes
Regenerative medicine
Review Paper
Stimuli
Surgical implants
Tissue engineering
Topography
Transplants & implants
Tumor necrosis factor-TNF
생물공학
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Title The latest techniques for inducing macrophage differentiation
URI https://link.springer.com/article/10.1007/s12257-024-00091-9
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Volume 29
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ispartofPNX Biotechnology and Bioprocess Engineering, 2024, 29(3), , pp.440-450
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