Nafamostat mesilate negatively regulates the metastasis of triple-negative breast cancer cells

• Published in: Archives of pharmacal research Vol. 41; no. 2; pp. 229 - 242
• Main Authors: Mander, Sunam, You, Dong-Joo, Park, Sumi, Kim, Dong Hwi, Yong, Hyo Jeong, Kim, Dong-Sik, Ahn, Curie, Kim, Yun-Hee, Seong, Jae Young, Hwang, Jong-Ik
• Format: Journal Article
• Language: English
• Published: Seoul Pharmaceutical Society of Korea 01.02.2018; 대한약학회
• Subjects: Medicine; Pharmacology/Toxicology; Pharmacy; Research Article; 약학; Metastasis; Triple negative breast cancer; Cell cycle; Nafamostat mesilate

Triple-negative breast cancer (TNBC) lacking of oestrogen receptor, progesterone receptor, and epidermal growth factor receptor type 2 is a highly malignant disease which results in a poor prognosis and rare treatment options. Despite the use of conventional chemotherapy for TNBC tumours, resistance...