Interaction of the carotid baroreflex, the muscle chemoreflex and the cardiopulmonary baroreflex in man during exercise

• Published in: The Physiologist Vol. 34; no. 1, Fe; pp. S118 - S120
• Main Authors: Eiken, O., Convertino, V. A., Doerr, D. F., Dudley, G. A., Morariu, G., Mekjavic, I. B.
• Format: Journal Article
• Language: English
• Published: Legacy CDMS 01.02.1991
• Subjects: Aerospace Medicine; Blood Circulation - physiology; Chemoreceptor Cells - physiology; Exercise - physiology; Humans; Lower Body Negative Pressure; Pressoreceptors - physiology; Reflex - physiology; Space life sciences; Weightlessness - adverse effects
• ISSN: 0031-9376; 1522-1202

The interaction of the muscle chemoreflex and the cardiopulmonary baroreflex with the carotid baroreflex in humans performing exercise was investigated in healthy subjects using specially designed exercise regimen and apparatus. Stimulation of the muscle chemoreflex was achieved by restricting blood flow in the exercising muscles by means of applying a pressure of 50 mm Hg, whereas cardiopulmonary baroreceptors were unloaded by employing LBNP of -20 mm Hg. The carotid baroreceptors were unloaded and stimulated by neck-pressure maneuvers (Sprenkle et al., 1986). Results showed that the cardiodecelerating capacity of the carotid baroreflex remains active during exercise, and may even be sensitized by the chemoreflex-induced increase in arterial pressure; but it is not affected by the cardiopulmonary baroreceptor activity.