A novel fluorescent reporter CDy1 enriches for neural stem cells derived from the murine brain

• Published in: Stem cells and development Vol. 22; no. 16; p. 2341
• Main Authors: Vukovic, Jana, Bedin, Anne-Sophie, Bartlett, Perry F, Osborne, Geoffrey W
• Format: Journal Article
• Language: English
• Published: United States 15.08.2013
• Subjects: Age Factors; Animals; Anthracenes - analysis; Biomarkers - analysis; Cell Differentiation; Female; Fluorescent Dyes - analysis; Hippocampus - cytology; Induced Pluripotent Stem Cells - cytology; Lateral Ventricles - cytology; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Morpholines - analysis; Neural Stem Cells - cytology; Neurogenesis; Spheroids, Cellular - cytology

Neurogenesis occurs continuously in two brain regions of adult mammals, underpinned by a pool of resident neural stem cells (NSCs) that can differentiate into all neural cell types. To advance our understanding of NSC function and to develop therapeutic and diagnostic approaches, it is important to...