Chemical Constituents from Sambucus adnata and Their Protein-Tyrosine Phosphatase 1B Inhibitory Activities

• Published in: Chemical & Pharmaceutical Bulletin Vol. 59; no. 11; pp. 1396 - 1399
• Main Authors: Tatsunori SASAKIa, Wei LIa, Haruna MORIMURAa, Songpei LIa, Qin LIb, Yoshihisa ASADAc, Kazuo KOIKEa
• Format: Journal Article
• Language: Japanese
• Published: Pharmaceutical Society of Japan 2011

The MeOH extract from the whole plants of Sambucus adnata has shown significant protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity. Chemical study on the extract resulted in the isolation of thirteen compounds, including a novel triterpene (1). The structure of 1 was determined to be 1α,3β-...