In vivo bioactivity of porous polyetheretherketone with a foamed surface

The in vivo bioactivity of porous polyetheretherketone (PEEK) with a foamed surface was evaluated using rabbit femoral bone. Cylindrical porous PEEK scaffolds, with pore diameter of 550 μm and porosity of 70%, were first prepared and immersed in 98% sulfuric acid, and then washed and immersed in 3 M...

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Bibliographic Details
Published inDental Materials Journal Vol. 36; no. 2; pp. 222 - 229
Main Authors Ayato HIEDA, Naoya UEMURA, Yoshiya HASHIMOTO, Isumi TODA, Shunsuke BABA
Format Journal Article
LanguageJapanese
Published Japanese Society for Dental Materials and Devices 01.04.2017
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Summary:The in vivo bioactivity of porous polyetheretherketone (PEEK) with a foamed surface was evaluated using rabbit femoral bone. Cylindrical porous PEEK scaffolds, with pore diameter of 550 μm and porosity of 70%, were first prepared and immersed in 98% sulfuric acid, and then washed and immersed in 3 M potassium carbonate solution used as a foaming reagent. Numerous open pores of various sizes, as well as new functional groups, were visualized on the treated PEEK surface by scanning electron microscopy and X-ray photoelectron spectroscopy, respectively. Micro computed tomography (micro-CT) showed that the volumetric density of treated PEEK was higher than that of bare PEEK at 8 weeks after surgery (p<0.05). Additionally, von Kossa staining indicated ingrowth of mature new bone tissue at 4 weeks relative to the bare PEEK group. Our data indicate that surface-treated PEEK exhibited improved bioactivity in vivo.
ISSN:0287-4547
1881-1361