Successful combination therapy with corticosteroids, biweekly intravenous pulse cyclophosphamide and cyclosporin A for acute interstitial pneumonia in patients with dermatomyositis : report of three cases

[summary] We report three patients with dermatomyositis (DM) complicated with acute interstitial pneumonia (AIP). All of them complained of fever and acutely worsening dyspnea and were treated immediately by combination therapies with pulse therapy with methylprednisone (mPSL) followed by corticoste...

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Published inJapanese Journal of Clinical Immunology Vol. 36; no. 2; pp. 122 - 128
Main Authors Akitake SUZUKI, Norikazu SHOJI, Eigo KIKUCHI, Kazuaki UEKUBO, Naoko AOKI, Yui SONODA, Hideyuki TORIGAI, Hiroyuki YAMASHITA, Kentaro FUJITA, Takahiro OKAI
Format Journal Article
LanguageJapanese
Published The Japan Society for Clinical Immunology 28.04.2013
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Abstract [summary] We report three patients with dermatomyositis (DM) complicated with acute interstitial pneumonia (AIP). All of them complained of fever and acutely worsening dyspnea and were treated immediately by combination therapies with pulse therapy with methylprednisone (mPSL) followed by corticosteroids, biweekly intravenous pulse cyclophosphamide (IVCY) and cyclosporine A (CSA). They recovered rapidly soon after an initiation of this combination regimen. Early intervention with aggressive combination therapy is life-saving for the treatment of AIP in patients with DM.
AbstractList [summary] We report three patients with dermatomyositis (DM) complicated with acute interstitial pneumonia (AIP). All of them complained of fever and acutely worsening dyspnea and were treated immediately by combination therapies with pulse therapy with methylprednisone (mPSL) followed by corticosteroids, biweekly intravenous pulse cyclophosphamide (IVCY) and cyclosporine A (CSA). They recovered rapidly soon after an initiation of this combination regimen. Early intervention with aggressive combination therapy is life-saving for the treatment of AIP in patients with DM.
Author Norikazu SHOJI
Kentaro FUJITA
Eigo KIKUCHI
Kazuaki UEKUBO
Hideyuki TORIGAI
Takahiro OKAI
Naoko AOKI
Akitake SUZUKI
Yui SONODA
Hiroyuki YAMASHITA
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  fullname: Takahiro OKAI
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CorporateAuthor Kawakita General Hospital
Center for Rheumatology and Joint Surgery
National Center for Global Health and Medicine
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Snippet [summary] We report three patients with dermatomyositis (DM) complicated with acute interstitial pneumonia (AIP). All of them complained of fever and acutely...
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Title Successful combination therapy with corticosteroids, biweekly intravenous pulse cyclophosphamide and cyclosporin A for acute interstitial pneumonia in patients with dermatomyositis : report of three cases
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