A randomized, open-label, multicenter study evaluating the efficacy of peginterferon alfa-2a versus interferon alfa-2a, in combination with ribavirin, in naïve and relapsed chronic hepatitis C patients

• Published in: Acta gastro-enterologica belgica Vol. 73; no. 2; p. 223
• Main Authors: Nevens, F, Van Vlierberghe, H, D'Heygere, E, Delwaide, J, Adler, M, Henrion, J, Lenaerts, A, Hendlisz, A, Michielsen, P, Bastens, B, Brenard, R, Laureys, A
• Format: Journal Article
• Language: English
• Published: Belgium 01.04.2010
• Subjects: Antiviral Agents - administration & dosage; Drug Therapy, Combination; Female; Hepatitis C, Chronic - drug therapy; Humans; Interferon-alpha - administration & dosage; Logistic Models; Male; Middle Aged; Polyethylene Glycols - administration & dosage; Prospective Studies; Recombinant Proteins; Ribavirin - administration & dosage; RNA, Viral - analysis; Treatment Outcome

A large multicenter trial to compare the efficacy of peginterferon alfa-2a with interferon alfa-2a, in combination with ribavirin, in chronic hepatitis C patients. Efficacy data for prior relapsers are reported because treatment recommendations for this patient population are not well defined. This...