대장암 환자의 옥살리플라틴(oxaliplatin) 유도 말초신경병증에 대한 약물유전학적 접근: 체계적 문헌고찰

• Published in: Journal of Korean biological nursing science Vol. 20; no. 2; pp. 55 - 66
• Main Authors: 안수정, 최소영, 정혜정, 추상희
• Format: Journal Article
• Language: Korean
• Published: 한국기초간호학회 31.05.2018
• Subjects: 간호학; 옥살리플라틴; 말초신경병증; Pharmacogenetics; Oxaliplatin; 대장암; Colorectal cancer; Peripheral neuropathy; 약물유전학

Purpose: Peripheral neuropathy is common among colorectal cancer (CRC) patients who undergo oxaliplatin-based (OXL) chemotherapy. A pharmacogenetic approach can be used to identify patients at high-risk of developing severe neuropathy. This type of approach can also help clinicians determine the bes...