소아청소년 양극성 장애의 임상 경과

• Published in: Soa--chʻŏngsonyŏn chŏngsin ŭihak = Journal of child & adolescent psychiatry Vol. 23; no. 1; pp. 3 - 7
• Main Authors: 강나리(Na-Ri Kang), 곽영숙(Young-Sook Kwack)
• Format: Journal Article
• Language: Korean
• Published: 대한소아청소년정신의학회 2012; 대한소아청소년 정신의학회
• Subjects: 정신과학; 소아; Pediatric Bipolar Disorder; 양극성 장애; Outcome; 임상경과; Clinical Course; 청소년
• ISSN: 1225-729X; 2233-9183

Objectives : The early onset of mood symptoms in bipolar disorder has been associated with poor outcomes in many studies. However, aspects of the clinical course of bipolar disorder in children and adolescents are controversial. The goal of this article is to review the clinical characteristics and longitudinal course of children and adolescents with bipolar disorders. Methods : Searches were conducted in MedLine, PsycINFO, KISS, and RISS using the terms phenomenology, clinical course, outcome, BPD, pediatric, children and adolescents. Twenty-one reports were selected : either original articles reporting symptoms and clinical characteristics of subjects (ages 5-18 years), or published articles in reviewed journals about bipolar disorder in children and adolescents. Results : Approximately 70% of subjects with bipolar disorder recovered from their index episode, and 50% had at least 1 syndromal recurrence, particularly depressive episodes. For 60% of the follow-up time, subjects had syndromal or subsyndromal symptoms with numerous changes in symptoms and shifts of polarity. Approximately 20% of BP-II subjects converted BP-I. Conclusion : Bipolar disorders in children and adolescents are characterized by episodic illness with subsyndromal and syndromal episodes with mainly depressive and mixed symptoms and rapid mood changes. Extensive follow-up time is needed to evaluate the continuity of bipolar disorder symptoms from childhood to adulthood.