구개골에 발생한 악성 Peripheral Nerve Sheath Tumor의 증례보고
The malignant peripheral nerve sheath tumor(MPNST) is an aggressive neoplasm and can either arise independently or result from malignant change in preexisting neurofibromatosis (von Recklinghausen's disease). Its histologic characteristics remain controversial, but currently it is believed that...
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Published in | Journal of the Korean Association of Oral and Maxillofacial Surgeons Vol. 30; no. 3; pp. 228 - 233 |
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Main Authors | , , , , |
Format | Journal Article |
Language | Korean |
Published |
대한구강악안면외과학회
30.06.2004
Korean Association Of Oral And Maxillofacial Surgeons |
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Abstract | The malignant peripheral nerve sheath tumor(MPNST) is an aggressive neoplasm and can either arise independently or result from malignant change in preexisting neurofibromatosis (von Recklinghausen's disease). Its histologic characteristics remain controversial, but currently it is believed that the schwann cell is the origin of the peripheral nerve sheath tumors. MPNST is an uncommon neoplasm of the head and neck region, and its presentation in the oral cavity is quite rare. In this study, we report a patient with a rare case of a MPNST involving the maxilla.
A 29-year-old female presented with a chief complaint of painless swelling with bleeding tendency on the left maxillary tuberosity area 2 months ago. Clinical examination showed a 5.0X3.0 cm2 sized, indurative swelling on the site. Conventional radiographs showed a relatively well-defined soft tissue mass involving the left maxillary sinus, and destruction of the anterior, posterolateral walls of the left maxillary sinus.
Subtotal maxillectomy and split-thickness skin graft from thigh were undertaken. In histochemical and immunohistochemical studies, the specimen revealed positive reactivities to Vimentin and S-100 protein. Final diagnosis was made as MPNST. KCI Citation Count: 0 |
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AbstractList | The malignant peripheral nerve sheath tumor(MPNST) is an aggressive neoplasm and can either arise independently or result from malignant change in preexisting neurofibromatosis (von Recklinghausen's disease). Its histologic characteristics remain controversial, but currently it is believed that the schwann cell is the origin of the peripheral nerve sheath tumors. MPNST is an uncommon neoplasm of the head and neck region, and its presentation in the oral cavity is quite rare. In this study, we report a patient with a rare case of a MPNST involving the maxilla.
A 29-year-old female presented with a chief complaint of painless swelling with bleeding tendency on the left maxillary tuberosity area 2 months ago. Clinical examination showed a 5.0X3.0 cm2 sized, indurative swelling on the site. Conventional radiographs showed a relatively well-defined soft tissue mass involving the left maxillary sinus, and destruction of the anterior, posterolateral walls of the left maxillary sinus.
Subtotal maxillectomy and split-thickness skin graft from thigh were undertaken. In histochemical and immunohistochemical studies, the specimen revealed positive reactivities to Vimentin and S-100 protein. Final diagnosis was made as MPNST. KCI Citation Count: 0 |
Author | 이현상(Hyun-Sang Lee) 김현창(Hyun-Chang Kim) 고승오(Seung-O Ko) 신효근(Hyo-Keun Shin) 권민수(Min-Su Kwon) |
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DocumentTitleAlternate | MALIGNANT PERIPHERAL NERVE SHEATH TUMOR ON PALATE: A CASE REPORT Malignant peripheral nerve sheath tumor on palate : A case report |
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Title | 구개골에 발생한 악성 Peripheral Nerve Sheath Tumor의 증례보고 |
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