한국인 폐결핵 환자에서 HLA-DRB1 및 -DQB1 유전자의 다형성에 관한 연구

• Published in: Tuberculosis and respiratory diseases Vol. 54; no. 4; pp. 367 - 377
• Main Authors: 박명희, Park Myeong Hui, 송은영, Song Eun Yeong, 권성연, Kwon Seong Yeon, 박혜진, Park Hye Jin, 한성구, Han Seong Gu, 심영수, Sim Yeong Su
• Format: Journal Article
• Language: Korean
• Published: 대한결핵 및 호흡기학회 30.04.2003; 대한결핵및호흡기학회
• Subjects: Drug-sensitive tuberculosis; HLA-DQB1; HLA-DRB1; Korean; Multidrug-resistant tuberculosis; Pulmonary tuberculosis; 내과학; Korean; Multidrug-resistant tuberculosis; Drug-sensitive tuberculosis; HLA-DRB1; Pulmonary tuberculosis; HLA-DQB1

Background : It is well known that only 10% of those infected with Mycobacterium tuberculosis actually develop clinical disease, indicating the existence of host genetic factors regulating disease expression. In this study, we investigated HLA-DRB1 and -DQB1 gene polymorphisms in Korean patients wit...