유전독성시험에 의한 녹용약침의 안전성 연구

• Published in: 大韓本草學會誌 Vol. 20; no. 2; pp. 1 - 6
• Main Authors: 변부형, Boo Hyeong Byun, 서부일, Bu Il Seo
• Format: Journal Article
• Language: Korean
• Published: 대한본초학회 30.06.2005
• Subjects: cell culture system; Cervi pantotrichum Cornu Herbal aqua-acupuncture solution; CPCHA; genetics; HeLa; NIH3T3; SW480; toxicity; 한의학; toxicity; HeLa; SW480; genetics; NIH3T3; Cervi pantotrichum Cornu Herbal aqua-acupuncture solution(CPCHA); cell culture system
• ISSN: 1229-1765; 2288-7199

Objectives : The purpose of this study is to investigate genetic toxicity of Cervi pantotrichum Cornu herbal acupuncture solution(CPCHA). Methods : In this study, a series of investigation have been carried out to analyze the effects of Cervi pantotrichum Cornu herball acupuncture solution(CPCHA) on colony forming ability of NIH3T3cells, Hela cells and adrenorectal coloncell for genetic toxicity test. Results and Conclusions : From the above results, it is suggested that Cervi pantotrichum Cornu herball acupuncture solution(CPCHA) was limited 0.5-10ug/ml by test. Cervi pantotrichum Cornu herball acupuncture solution(CPCHA) did not exert the protective role to the genetic toxicity in kinds of cell lines used in this study. From these results, Cervi pantotrichum Cornu herbal aqua-acupuncture solution needs further study to prove it's function in cell culture system.