임상연구의 설계 및 연구윤리

• Published in: Journal of the Korean Society of Biological Psychiatry Vol. 19; no. 4; pp. 172 - 178
• Main Authors: 장재승, 이선이, 하태현, 윤인영, 하규섭, Chang, Jae Seung, Lee, Sunny, Ha, Tae Hyon, Yoon, In-Young, Ha, Kyooseob
• Format: Journal Article
• Language: Korean
• Published: 대한생물정신의학회 01.11.2012
• Subjects: 정신과학
• ISSN: 1225-8709; 2005-7571

Data from clinical studies are needed for psychiatrists to make quick and scientific decisions based on the best available evidence in clinical settings. Various methods of clinical studies are useful for clinicians to have reliable answers to unmet clinical needs. Although randomized controlled trials may provide high-quality information about major issues, well-designed, naturalistic and observational studies often give us unbiased explanation for real-world phenomena. Adequate selection of clinical variables and appropriate number of participants are key factors of well-designed clinical studies. Statistical methods can add an extra dimension to initial design of clinical studies. Given ethical issues in clinical studies on psychiatric disorders, special regards should be paid to participants' ability to provide informed consents. New strategies of clinical studies need to be developed to meet clinical needs and protect the rights and welfare of study participants.