Hederagenin의 뼈 형성 관련 작용 기전 연구

• Published in: Journal of nutrition and health Vol. 55; no. 6; pp. 617 - 629
• Main Authors: 서현주(Hyun-Ju Seo), 권인숙(In-Sook Kwun), 권재희(Jaehee Kwon), 심예진(Yejin Sim), 조영은(Young-Eun Cho)
• Format: Journal Article
• Language: Korean
• Published: 한국영양학회 2022
• Subjects: BMP2 protein; hederagenin; osteoblasts; osteoporosis; SMAD1 protein

Purpose: Osteoporosis is characterized by structural deterioration of the bone tissue because of the loss of osteoblastic activity or the increase in osteoclastic activity, resulting in bone fragility and an increased risk of fractures. Hederagenin (Hed) is a pentacyclic triterpenoid saponin isolate...