만성 기침의 새로운 임상 접근법: 최근 진료 지침을 기반으로

• Published in: The Korean journal of medicine Vol. 94; no. 6; pp. 471 - 484
• Main Authors: 송우정, Woo-jung Song, 김상훈, Sang-hoon Kim
• Format: Journal Article
• Language: Korean
• Published: 대한내과학회 01.12.2019
• Subjects: Cough; Guideline; 가이드라인; 기침; 내과학
• ISSN: 1738-9364; 2289-0769
• DOI: 10.3904/kjm.2019.94.6.471

The cough reflex is a vital protective mechanism for the lower airways against aspiration, but when dysregulated, it becomes a clinical problem. Indeed, chronic cough is an important clinical issue as it is common in the general population and causes consid-erable morbidity. Anatomic diagnostic protocols were the first breakthrough in the management of patients with chronic cough; however, as systematic approaches are not always successful, a new paradigm of cough hypersensitivity syndrome has been proposed. The introduction of this paradigm has provided new opportunities for managing chronic cough, including development of new cough assessment tools and effective cough control therapies. However, it also warranted re-appraisal of existing clinical evi-dence and refinement of our clinical pathways. Against this background, international and domestic evidence-based practice guide-lines based on a strict methodology have been published recently. In this review, we introduce clinical approaches based on the con-cept of cough hypersensitivity syndrome and discuss key aspects of recently published guidelines for chronic cough in adults. (Korean J Med 2019;94:471-484)