근접 치료에서 역방향 치료 계획의 선량분포 계산 가속화 방법

With the recent development of static and dynamic modulated brachytherapy methods in brachytherapy, which use radiation shielding to modulate the dose distribution to deliver the dose, the amount of parameters and data required for dose calculation in inverse treatment planning and treatment plan op...

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Published in한국방사선학회 논문지 Vol. 17; no. 5; pp. 633 - 640
Main Authors 조병두, Byungdu Jo
Format Journal Article
LanguageKorean
Published 한국방사선학회 30.10.2023
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ISSN1976-0620

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Abstract With the recent development of static and dynamic modulated brachytherapy methods in brachytherapy, which use radiation shielding to modulate the dose distribution to deliver the dose, the amount of parameters and data required for dose calculation in inverse treatment planning and treatment plan optimization algorithms suitable for new directional beam intensity modulated brachytherapy is increasing. Although intensity-modulated brachytherapy enables accurate dose delivery of radiation, the increased amount of parameters and data increases the elapsed time required for dose calculation. In this study, a GPU-based CUDA-accelerated dose calculation algorithm was constructed to reduce the increase in dose calculation elapsed time. The acceleration of the calculation process was achieved by parallelizing the calculation of the system matrix of the volume of interest and the dose calculation. The developed algorithms were all performed in the same computing environment with an Intel (3.7 GHz, 6-core) CPU and a single NVIDIA GTX 1080ti graphics card, and the dose calculation time was evaluated by measuring only the dose calculation time, excluding the additional time required for loading data from disk and preprocessing operations. The results showed that the accelerated algorithm reduced the dose calculation time by about 30 times compared to the CPU-only calculation. The accelerated dose calculation algorithm can be expected to speed up treatment planning when new treatment plans need to be created to account for daily variations in applicator movement, such as in adaptive radiotherapy, or when dose calculation needs to account for changing parameters, such as in dynamically modulated brachytherapy.
AbstractList With the recent development of static and dynamic modulated brachytherapy methods in brachytherapy, which use radiation shielding to modulate the dose distribution to deliver the dose, the amount of parameters and data required for dose calculation in inverse treatment planning and treatment plan optimization algorithms suitable for new directional beam intensity modulated brachytherapy is increasing. Although intensity-modulated brachytherapy enables accurate dose delivery of radiation, the increased amount of parameters and data increases the elapsed time required for dose calculation. In this study, a GPU-based CUDA-accelerated dose calculation algorithm was constructed to reduce the increase in dose calculation elapsed time. The acceleration of the calculation process was achieved by parallelizing the calculation of the system matrix of the volume of interest and the dose calculation. The developed algorithms were all performed in the same computing environment with an Intel (3.7 GHz, 6-core) CPU and a single NVIDIA GTX 1080ti graphics card, and the dose calculation time was evaluated by measuring only the dose calculation time, excluding the additional time required for loading data from disk and preprocessing operations. The results showed that the accelerated algorithm reduced the dose calculation time by about 30 times compared to the CPU-only calculation. The accelerated dose calculation algorithm can be expected to speed up treatment planning when new treatment plans need to be created to account for daily variations in applicator movement, such as in adaptive radiotherapy, or when dose calculation needs to account for changing parameters, such as in dynamically modulated brachytherapy.
With the recent development of static and dynamic modulated brachytherapy methods in brachytherapy, which use radiation shielding to modulate the dose distribution to deliver the dose, the amount of parameters and data required for dose calculation in inverse treatment planning and treatment plan optimization algorithms suitable for new directional beam intensity modulated brachytherapy is increasing. Although intensity-modulated brachytherapy enables accurate dose delivery of radiation, the increased amount of parameters and data increases the elapsed time required for dose calculation. In this study, a GPU-based CUDA-accelerated dose calculation algorithm was constructed to reduce the increase in dose calculation elapsed time. The acceleration of the calculation process was achieved by parallelizing the calculation of the system matrix of the volume of interest and the dose calculation. The developed algorithms were all performed in the same computing environment with an Intel (3.7 GHz, 6-core) CPU and a single NVIDIA GTX 1080ti graphics card, and the dose calculation time was evaluated by measuring only the dose calculation time, excluding the additional time required for loading data from disk and preprocessing operations. The results showed that the accelerated algorithm reduced the dose calculation time by about 30 times compared to the CPU-only calculation. The accelerated dose calculation algorithm can be expected to speed up treatment planning when new treatment plans need to be created to account for daily variations in applicator movement, such as in adaptive radiotherapy, or when dose calculation needs to account for changing parameters, such as in dynamically modulated brachytherapy. 최근 근접 치료에서 방사선 차폐막을 사용하여 선량 분포를 변조하여 선량을 전달하는 정적 및 동적 변조 근접 치료 방법이 개발됨에 따라 새로운 방향성 빔 세기 변조 근접 치료에 적합한 역방향 치료 계획 및 치료 계획 최적화 알고리즘에서 선량 계산에 필요한 파라미터 및 데이터의 양이 증가하고 있다. 세기 변조 근접 치료는 방사선의 정확한 선량 전달이 가능하지만, 파라미터와 데이터의 양이 증가하기 때문에 선량 계산에 필요한 경과 시간이 증가한다. 본 연구에서는 선량 계산 경과 시간의 증가를 줄이기 위해 그래픽 카드 기반의 CUDA 가속 선량 계산 알고리즘을 구축하였다. 계산 과정의 가속화 방법은 관심 체적의 시스템 행렬 계산 및 선량 계산의 병렬화를 이용하여 진행하였다. 개발된 알고리즘은 모두 인텔(3.7GHz, 6코어) CPU와 단일 NVIDIA GTX 1080ti 그래픽 카드가 장착된 동일한 컴퓨팅 환경에서 수행하였으며, 선량 계산 시간은 디스크에서 데이터를 불러오고 전처리를 위한 작업 등의 추가 적으로 필요한 시간은 제외하고 선량 계산 시간만 측정하여 평가하였다. 그 결과 가속화된 알고리즘은 CPU로만 계산할 때보다 선량 계산 시간이 약 30배 단축된 것으로 나타났다. 가속화된 선량 계산 알고리즘은 적응방사선치료와 같이 매일 변화되는 어플리케이터의 움직임을 고려하여 새로운 치료 계획을 수립해야 하는 경우나 동적 변조 근접 치료와 같이 선량 계산에 변화되는 파라미터를 고려해야 하는 경우 치료 계획 수립 속도를 높일 수 있을 것으로 판단된다.
Author 조병두
Byungdu Jo
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SubjectTerms Accelerated Algorithms
Brachytherapy
Dose Calculation
Inverse Treatment Planning
Title 근접 치료에서 역방향 치료 계획의 선량분포 계산 가속화 방법
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