Yeast Surface Display of Capsid Protein VP7 of Grass Carp Reovirus: Fundamental Investigation for the Development of Vaccine Against Hemorrhagic Disease

• Published in: Journal of microbiology and biotechnology Vol. 25; no. 12; pp. 2135 - 2145
• Main Authors: Luo, Shaoxiang, Yan, Liming, Zhang, Xiaohua, Yuan, Li, Fang, Qin, Zhang, Yong-An, Dai, Heping
• Format: Journal Article
• Language: Korean
• Published: 한국미생물생명공학회 31.12.2015
• Subjects: grass carp reovirus; protein VP7; Yeast surface display; yeast-based vaccine; yeast-based vaccine; grass carp reovirus; protein VP7; Yeast surface display

VP7, an outer capsid protein of grass carp reovirus (GCRV), was expressed and displayed on the surface of Saccharomyces cerevisiae for developing an efficient vaccine against hemorrhagic disease of grass carp. The result of flow cytometry analysis indicated that protein VP7 could be displayed on the...