The Role of Simulation and Scheduling Tools in the Development and Manufacturing of Active Pharmaceutical Ingredients

• Published in: Chemical Engineering in the Pharmaceutical Industry p. 1
• Main Authors: Petrides, Demetri, Koulouris, Alexandros, Siletti, Charles, Jiménez, José O, Lagonikos, Pericles T
• Format: Book Chapter
• Language: English
• Published: Hoboken, NJ, USA John Wiley & Sons 2011; John Wiley & Sons, Inc
• Subjects: Chemistry & Chemical Engineering; General References; modeling and analysis of API manufacturing process; Pharmaceuticals; Pharmaceuticals, Cosmetics & Toiletries; production scheduling and sample scheduling recipe; role of simulation and scheduling tools ‐ in active pharmaceutical ingredient development and manufacture

This chapter contains sections titled: Introduction Commercially Available Simulation and Scheduling Tools Modeling and Analysis of an API Manufacturing Process Uncertainty and Variability Analysis Production Scheduling Capacity Analysis and Production Planning Summary References