Actinomycetes The Antibiotics Producers

• Format: eBook
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: (p)ppGpp; A40926; Actinoallomurus; Actinobacteria; actinomycetes; acyltransferases; Amycolatopsis; antibiotic; antibiotics; antibiotics polyethers; aromatic polyketide; benz[a]naphthacene quinone; biogeography; biological activity; Biology, life sciences; biosynthesis; biosynthetic gene cluster; Cave microbiology; chemical ecology; comparative genomics; culture-based approaches; cyclases; dalbavancin; dbv cluster; dereplication; differentiation; diversification; drug discovery; elicitors; engineering; extended polyketide chain; FK506; genome mining; geomicrobiology; glycopeptide antibiotics; Illumina sequencing; LAL; liquid cultures; LuxR solo; lysolipin; Mathematics and Science; metabolomics; metagenomics; microbiome diversity; minimal PKS II; morphology; n/a; natural products; new bioactive compounds; novel compounds; omics; pentacyclic angular polyphenol; physical and chemical properties; physicochemical screening; polyadenylation; polyketide synthases; polyketides; polynucleotide phosphorylase; promoter; rare Actinobacteria; rare actinomycetes; Reference, Information and Interdisciplinary subjects; regulation; regulatory genes; Research and information: general; resistance; ribonuclease; rishirilide; RNA decay; screening; secondary metabolism; secondary metabolite; secondary metabolite biosynthetic gene clusters; secondary metabolites; secretion pathways; secretory proteins; siderophore; signal peptides; SMGC; specialized metabolites; strain; Streptomyces; Streptomyces lividans; Streptomyces tsukubaensis; StrR; structural diversity; symbiosis; tacrolimus; teicoplanin; tridecaketide; unculturability; van resistance genes; β-lactamase; β-lactamase inhibitor
• ISBN: 3039369113; 3039369105; 9783039369102; 9783039369119
• DOI: 10.3390/books978-3-03936-911-9

Beyond being the most important natural compound source, actinomycetes are the origin of up to two-thirds of all clinically used antibiotics. Currently, new antimicrobials are urgently needed, as infections caused by antibiotic-resistant pathogens are on the rise. In the identification of new antibi...