The Alveolar Epithelium Mechanisms of Injury and Repair

• Format: eBook
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: 3D reconstruction; acinar micromechanics; acute lung injury; acute mountain sickness; air-blood barrier; air-liquid interface; alveolar epithelial cells; alveolar epithelium; alveolar fluid; alveolar lining layer; alveolar micromechanics; alveolar septal composition; alveoli; alveolus; atelectrauma; autophagy; Biology, life sciences; bleomycin-induced lung injury; bovine; carbon dioxide; chlamydia; dietary sugar; endoplasmic reticulum; epithelial cell dysfunction; epithelium; extracellular matrix remodeling; focused ion beam scanning electron microscopy; glycocalyx; GSK-3β; high-altitude pulmonary edema; hypercapnia; hyperglycemia; inflammatory signaling; JAM-A; K-ATPase; lung; lung injury; lung mechanics; lung regeneration; lysosomal membrane permeability; lysosome; Mathematics and Science; microRNA-21; mitochondria; mouse lung; necrotizing; oxygen diffusion limitation; P2X7 receptor; physical activity; pneumocyte; pneumonia; protein oxidation; pulmonary fibrosis; Reference, Information and Interdisciplinary subjects; regeneration; Research and information: general; sodium transport; stem cell exhaustion; structural remodeling; surfactant; surfactant protein B; type 1 alveolar epithelial cell; type 2 alveolar epithelial cell

Alveolar epithelial cells (AECs) of the lung are important contributors to pulmonary immune functions and to pulmonary development and alveolar repair mechanisms following lung injury. AECI, together with the capillary endothelium, form the extremely thin barrier between alveolar air and blood. AECI...