Rotenone- 및 MPTP-유도 파킨슨병 동물 모델에서 돌외 에탄올 추출물의 Dopamine 신경세포 보호작용

The neuroprotective effects of herbal ethanol extract (GP-EX) from Gynostemma pentaphyllum on dopamine neurons in animal model of Parkinson's disease (PD) were investigated. Rats and mice were administered with rotenone (2.5 mg/kg) for 28 days and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (M...

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Bibliographic Details
Published inYaghag-hoi-ji Vol. 57; no. 2; pp. 77 - 86
Main Authors 서광훈, 최현숙, 신건성, 조정정, 김승환, 황방연, 이종길, 이명구
Format Journal Article
LanguageKorean
Published The Pharmaceutical Society Of Korea 2013
대한약학회
Subjects
약학
animal model of Parkinson's disease
L-DOPA
tyrosine hydrox-ylase
dopamine neuron
rotenone
Gynostemma pentaphyllum
MPTP
tyrosine hydroxylase
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  • 재료 및 실험방법 실험결과 고 찰 결 론 감사의 말씀 참고문헌