1998년부터 2000년 사이 경북지역 농장의 돼지로부터 분리한 Salmonella enterica Serovar Typhimurium의 역학조사

• Published in: Journal of bacteriology and virology Vol. 35; no. 2; pp. 87 - 92
• Main Authors: 설성용, Sung Yong Seol, 김기영, Ki Young Kim, 정영숙, Young Sook Jeong, 강희영, Hee Young Kang, 유학선, Hak Sun Yu, 김봉환, Bong Hwan Kim, 조동택, Dong Taek Cho, 이유철, Yoo Chul Lee, 이제철, Je Chul Lee
• Format: Journal Article
• Language: Korean
• Published: 대한바이러스학회 2005; 대한미생물학회
• Subjects: Antimicrobial resistance; Epidemiology; PFGE; Plasmid; Salmonella enterica serovar Typhimurium; 생물학; Plasmid; PFGE; Salmonella enterica serovar Typhimurium; Antimicrobial resistance; Epidemiology
• ISSN: 1598-2467; 2093-0429

A total of 40 Salmolella enterica serovar Typhimurium (S. typhimurium) strains were isolate d from clinical specimens of swine at 10 farms in Kyungpook province from 1998 to 2000. We investigated the clonal relationship of S. typhimurium isolates by antimicrobial susceptibility, plasmid profile, and Southern hybridization analysis with tetA, and pulsed-field gel electrophoresis (PFGE). All S. typhimurium isolates showed identical biochemical characteristics and were resistant to tetracycline, streptomycin, and sulfamehtoxazole. They were classified into 5 groups by antimicrobial resistance patterns. S. typhimurium isolates carried 3 to 5 plasmids and were classified into 5 groups by plasmid profiles. Southern hybridization showed that tetA gene was located in 21kb of plasmid. S. typhimurium isolates from 9 different farms showed identical or similar PFGE patterns, which indicates clonal origin of the strains. All S. typhimurium isolates, except one isolate from 1998, seemed to belong to be one clone by the combination of three epidemiological typing methods. These data demonstrated that a specific clone of Salmolella enterica serovar Typhimurium was widely spread in swine farms in Kyungpook province.