Peptides for Health Benefits 2019 Volume 2
In recent years, peptides have received increased interest from the pharmaceutical industry. The high potency, specificity, and safety profile are the main strengths of bioactive peptides as new and promising therapies that may fill the gap between small molecules and protein drugs. These positive a...
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Format | eBook |
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Language | English |
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Basel, Switzerland
MDPI - Multidisciplinary Digital Publishing Institute
2020
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Abstract | In recent years, peptides have received increased interest from the pharmaceutical industry. The high potency, specificity, and safety profile are the main strengths of bioactive peptides as new and promising therapies that may fill the gap between small molecules and protein drugs. These positive attributes have renewed interest in the discovery, optimization, and development of peptides as pharmacological therapy. Among bioactive peptides, those released from food sources have acquired importance as nutraceutical and active components in functional foods because they possess regulatory functions that can lead to health benefits. This Special Issue covers a selection of recent research papers and reviews in the field of bioactive peptides. It covers all aspects of peptide research in relation to health promotion. In particular, it emphasizes current knowledge and research trends concerning bioactive peptides, including identification and quantification of peptides from new sources, methods for their production and purification, structure–function relationships, mechanisms of action, in vitro and in vivo assays for the evaluation of their bioactivity, physiological evidence to support health benefits, and peptide stability and bioavailability. Papers regarding the development of new drugs, functional foods, or nutraceuticals based on bioactive peptides were also considered. |
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AbstractList | In recent years, peptides have received increased interest from the pharmaceutical industry. The high potency, specificity, and safety profile are the main strengths of bioactive peptides as new and promising therapies that may fill the gap between small molecules and protein drugs. These positive attributes have renewed interest in the discovery, optimization, and development of peptides as pharmacological therapy. Among bioactive peptides, those released from food sources have acquired importance as nutraceutical and active components in functional foods because they possess regulatory functions that can lead to health benefits. This Special Issue covers a selection of recent research papers and reviews in the field of bioactive peptides. It covers all aspects of peptide research in relation to health promotion. In particular, it emphasizes current knowledge and research trends concerning bioactive peptides, including identification and quantification of peptides from new sources, methods for their production and purification, structure–function relationships, mechanisms of action, in vitro and in vivo assays for the evaluation of their bioactivity, physiological evidence to support health benefits, and peptide stability and bioavailability. Papers regarding the development of new drugs, functional foods, or nutraceuticals based on bioactive peptides were also considered. |
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Editor | Hernández-Ledesma, Blanca Martínez-Villaluenga, Cristina |
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SubjectTerms | ACE-inhibitory activity acrylamide airway inflammation alcalase hydrolysate Alzheimer’s disease AMD AMP identification and design amyloid amyloid fibrils and endothelial regeneration angiogenic precursor cells angiotensin I converting enzyme anti-biofilm peptides anti-inflammatory antibiotic resistance antifungal activity antigen-specific antihypertensive peptides antimicrobial peptide antimicrobial peptides antimicrobial peptides (AMPs) antimicrobial resistance antioxidant activity antioxidant peptide antiproliferative assay antisepsis apolipoprotein E arthritis asthma Aβ peptide bioactive peptide bioactive peptides Biology, life sciences biomarkers BIOPEP-UWM database biosynthesis bone erosion cancer antigen cancer stem cells cartilage destruction cathelicidins Cec-analogs Cecropins central nervous system diseases chemoprevention Chlorella sorokiniana chronic diseases Clostridioides difficile CNV collagen collagen peptide colorectal cancer combinatorial library confocal microscopy conjugation copper Crassostrea angulata cryptides CXCR3 cystic fibrosis cytoprotective effect defensins diseases docetaxel doxorubicin dry-cured pork ham dyslipidemia endothelial dysfunction endothelial progenitor cells energy expenditure enteric nervous system enzyme extra domain B fermentation fetal bovine serum (FBS) fibroblasts fibronectin Fmoc/tBu food intake regulation food-derived foods formyl peptide receptors FPYLRH fresh tissue functional food galanin gender differences glioma GPR10 Histatin-5 host defense peptides Hs02 human antimicrobial peptides human keratinocytes humanized mouse hybrid peptide hydrolysis hydroxyprolyl-glycine (Hyp-Gly) hyperglycemia hypertension immune checkpoint inhibitor immune response immune suppression immunomodulant in silico In situ tetramer staining inflammation inflammatory bowel disease insects intragenic antimicrobial peptide Lactoferricin B (Lfcin B) library design ligands lunasin Mathematics and Science MDA MDR infectious diseases membrane activity MHC tetramer migration miiuy croaker (Miichthys miiuy) mode of action molecular blind docking molecular docking molecular weight monocyte MRSA multimeric peptides mutagenesis n/a nano liquid chromatography tandem mass spectrometry (nanoLC–nanoESI MS/MS) neuroprotection neurotensin NF-κB non-atopic asthma nutraceuticals nutrition obesity oral delivery osteostatin oxidative stress pegylated glucagon-like peptide 1 peptide peptide antibiotics peptide vaccine peptide–drug conjugate physico-chemical properties PI3K/Akt pathway pidotimod pig piscidins platelets polymicrobial biofilms pro-inflammatory pro-inflammatory cytokines prolactin-releasing peptide prolyl-hydroxyproline (Pro-Hyp) prostate cancer protection ability proteolysis proteome microarray proteomics pseudin-2 Pseudomonas aeruginosa pulmonary emphysema Reference, Information and Interdisciplinary subjects Research and information: general RF-amide peptides rheumatic diseases screening sheepskin signaling Sjögren’s syndrome SMILES code solid-phase synthesis sPLA2 Staphylococcus aureus stomach swim bladder synergistic effects synergy T cell T cells targeting temporin therapeutic potential type 1 diabetes vasoactive intestinal peptide VEGFR1 velvet antler VPAC1 receptor VPAC2 receptor whey peptides Αβ oligomer |
Subtitle | Volume 2 |
Title | Peptides for Health Benefits 2019 |
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