Alpha 1-adrenergic receptors in cardiac ventrienles of Dahl rats

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Published inShinzo Vol. 27; no. Supplement2; pp. 5 - 10
Main Authors Hayashi, Shuichi, Umemura, Satoshi, Tohyama, Shin-ichi, Shindo, Tadashi, Nakagawa, Mitsuru, Shiba, Kohsuke, Harada, Koki, Shigemasa, Tomohiko, Fukui, Kazuki, Ishii, Masao
Format Journal Article
LanguageJapanese
Published Japan Heart Foundation 25.05.1995
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Author Nakagawa, Mitsuru
Shigemasa, Tomohiko
Hayashi, Shuichi
Tohyama, Shin-ichi
Ishii, Masao
Harada, Koki
Shindo, Tadashi
Fukui, Kazuki
Shiba, Kohsuke
Umemura, Satoshi
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  fullname: Hayashi, Shuichi
  organization: Kanagawa Prefectural Cardiovascular and Respiratory Center
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  fullname: Umemura, Satoshi
  organization: Second Department of Internal Medicine, Yokohama City University School of Medicine
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  fullname: Tohyama, Shin-ichi
  organization: Kanagawa Prefectural Cardiovascular and Respiratory Center
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  fullname: Shindo, Tadashi
  organization: Kanagawa Prefectural Cardiovascular and Respiratory Center
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  fullname: Nakagawa, Mitsuru
  organization: Kanagawa Prefectural Cardiovascular and Respiratory Center
– sequence: 6
  fullname: Shiba, Kohsuke
  organization: Kanagawa Prefectural Cardiovascular and Respiratory Center
– sequence: 7
  fullname: Harada, Koki
  organization: Kanagawa Prefectural Cardiovascular and Respiratory Center
– sequence: 8
  fullname: Shigemasa, Tomohiko
  organization: Kanagawa Prefectural Cardiovascular and Respiratory Center
– sequence: 9
  fullname: Fukui, Kazuki
  organization: Kanagawa Prefectural Cardiovascular and Respiratory Center
– sequence: 10
  fullname: Ishii, Masao
  organization: Second Department of Internal Medicine, Yokohama City University School of Medicine
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References 12) Bbhm M, Mende U, Schmitz W, Scholz H: Increased sensitivity to ar-adrenoceptor stimulation but intact purinergic and hypertrophy of spontaneously hypertensive rats. Naunyn-Schmiedeberg's Arch Pharmacol 1986 ; 333 : 284-289
15) Kimball KA, Cornett LE, Steifen E, Kennedy RH : Aging changes in cardiac a1-adrenoceptor responsiveness and expression. Eur J Pharmacol 1991 ; 208 : 231-238
5) Hanna MK, PH Khairallah A: Alterations of myocardial a, -adrenergic receptors in hypertensive cardiac hypertrophy in the rat. Arch Int Pharmacodyn 1986 ; 283 : 80-93
16) Yamada 5, Isogai M, Okudaira H, Hayashi E: Correlation between cholinesterase inhibition and reduction in muscarinic receptors and choline uptake by repeated diisopropylfluorophosphate administration : antagonism by physostigmine and atropine. J Pharmacol Exp Ther 1983 ; 226 : 519-525
19) Lezin E, Simonet L, Pravenec M, et al : Hyper tensive strains and normntensive contrn1 strains How closely are they related ? Hypertension 1992 ; 19 : 419-424
1) Terzic A, Puceat M, Vassort G, Vogel S: Cardiac ai -adrenoceptors : An overview. Pharmacol rev 1993 ; 45 : 147-175
11) Yamada S, Henry I Yamamura, Roeske WR : Ontogeny of mammalian cardiac a1-adrenergic receptors. Eur J Pharmacol 1980 ; 68 : 217-221
9) Yamaguchi S, Umemura S, Iwamoto T, Kobayashi 5, Tamura K, Takagi N, Ishii M: DNA fingerprint analysis of Dahl-Iwai saltsensitive rats (S) and salt-resistant rats (R) . Life Sci 1994 ; 55 : 701-705
2) Simpson PC : Norepinephrine-stimulated hypertrophy of cultured rat myocardial cells is an ai -adrenergic response. J Clin Invest 1983 ; 72 : 732-738
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8) Michel MC, Kanczik R, Khamssi M, et al : and fl-adrenoceptors g-adrenoceptors in hypertension. Cardiac and renal al-, fly-, and A -adrenoceptors in rat models of acqured hypertension. J Cardiovasc Pharmacol 1989 ; 13 : 421-431
6) Mccaughran JA Jr, Juno CJ, O'malley E: Differential ontogeny of a1-adrenergic and cholinergic receptor sites in the atria and ventricles of the inbred Dahl hypertensionsensitive (S/JR) and-resistant (R/JR) rat. J Autonom Nery Syst 1987 ; 20 : 207-220
3) BOhm M, Beukelmann D, Diet F, Feiler G, Lohse MJ, Eedmann E: Properties of cardiac alpha-and beta-adrenoceptors in spontaneously hypertensive rats. Naunyn-Schmiedeberg's Arch Pharmacol 1988 ; 338 : 383-391
10) Iwai J, Heine M: Dahl salt-sensitive rats and human essential hypertension. J Hypertens 1986 ; 4 (Suppl 3) : S 29-S 31
17) Sakaue M, Hoffman BB : Glucocorticoid5 induce transcription and expression of the a, E adrenergic receptor gene in DTTI MF-2 smooth muscle cells. J Oin Invest 1991 ; 88 : 385-389
18) Lezin EM, Pravenec M, Wong A, et al : Genetic contamination of Dahl SS/Jr rats impact or studies of salt-sensitive hypertension. Hyperten sion 1994 ; 23 : 786-790
7) Mccaughran JA Jr, Juno CJ, Friedman R: Pre-and neonatal exposure of the Dahl rat to NaC1 : development and regional distribution of myocardial ar-adrenergic and cholinergic re- ceptor sites. J Autonom Nery Syst 1986 ; 16 : 137-152
20) Lacsmm, Morady F, Swan H JC : Myocardial hypertrophy produced by chronic infusion of subhypertensive doses of norepinephrine in the dog. Chest 1973 ; 64 : 75-78
4) Kagiya T, Hori M, Iwakura K, Iwai K, Watanabe Y, Uchida H, Kitabatake A, Inoue M, Kamada T: Role of increased ai -adrenergic activity in cardiomyopathic Syrian hamster. Am J Physiol 1991 ; 260 : H 80-88
21) Larson DF, Copeland JG, Haddock Russel D: Catecholamine-induced cardiac hypertrophy in a denervated, hemodynamically non-stressed heart transplant. Life Sci 1985 ; 36 : 2477-1489
14) Del Balzo U, Rosen MR, Malfatto G, Kaplan LM, Steinberg SF : Specific a, -adrenergic receptor subtypes modulate catecholamine-induced increases and decreases in ventricular automaticity. Circ Res 1990 ; 67 : 1535-1551
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SubjectTerms Alpha 1-adrenergic receptor
cardica ventricule
Dahl rat
Title Alpha 1-adrenergic receptors in cardiac ventrienles of Dahl rats
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