Synthesis of a Novel Dual Inhibitor of Thromboxane A2 Synthetase and 5-Lipoxygenase (E3040) via the Direct Coupling Reaction of Hydroquinone with 3-Pyridinecarboealdehyde
Synthesis of a novel dual inhibitor of thromboxane A2 synthetase and 5-lipoxygenase, 5, 7-dimethyl-6-hydroxy-2-methylamino-4-(3-pyridylmethyl)benzothiazole (E3040), was accomplished via a new coupling reaction, in which a key intermediate, (3, 6-dihydroxy-2, 4-dimethylphenyl)-(3-pyridyl)methanol, wa...
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Published in | Chemical & pharmaceutical bulletin Vol. 43; no. 10; pp. 1614 - 1616 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Tokyo
The Pharmaceutical Society of Japan
15.10.1995
Japan Science and Technology Agency |
Subjects | |
Online Access | Get full text |
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