Molecular basis of transient receptor potential channels in glioma
Ion channels have been suggested as hallmarks for cancer. This review provides an overview of transient receptor potential(TRP) channels with respect to their identification and function in glioma. We conclude by discussing some outstanding questions and future directions in the study of TRP channel...
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| Published in | Progress in Neuro-Oncology Vol. 27; no. 1; pp. 5 - 16 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
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Kinki Brain Tumor Pathology Conference
31.03.2020
近畿脳腫瘍病理検討会 |
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| Online Access | Get full text |
| ISSN | 1880-0742 2187-0551 |
| DOI | 10.11452/neurooncology.27.1_5 |
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| Abstract | Ion channels have been suggested as hallmarks for cancer. This review provides an overview of transient receptor potential(TRP) channels with respect to their identification and function in glioma. We conclude by discussing some outstanding questions and future directions in the study of TRP channels for the treatment of malignant glioma. |
|---|---|
| AbstractList | Ion channels have been suggested as hallmarks for cancer. This review provides an overview of transient receptor potential(TRP) channels with respect to their identification and function in glioma. We conclude by discussing some outstanding questions and future directions in the study of TRP channels for the treatment of malignant glioma. |
| Author | Hayashi, Mikio Nonaka, Masahiro Iwata, Ryoichi Asai, Akio Hashiba, Tetsuo |
| Author_FL | 林 美樹夫 岩田 亮一 埜中 正博 淺井 昭雄 羽柴 哲夫 |
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| Author_xml | – sequence: 1 fullname: Hayashi, Mikio organization: Department of Cell Physiology Institute of Biomedical Science Kansai Medical University – sequence: 1 fullname: Asai, Akio organization: Department of Neurosurgery Kansai Medical University – sequence: 1 fullname: Iwata, Ryoichi organization: Department of Neurosurgery Kansai Medical University – sequence: 1 fullname: Hashiba, Tetsuo organization: Department of Neurosurgery Kansai Medical University – sequence: 1 fullname: Nonaka, Masahiro organization: Department of Neurosurgery Kansai Medical University |
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| Copyright | 2020 Kinki Brain Tumor Pathology Conference |
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Int J Physiol Pathophysiol Pharmacol 9: 8-15, (2017). 53. Morelli MB, Nabissi M, Amantini C, Tomassoni D, Rossi F, Cardinali C, Santoni M, Arcella A, Oliva MA, Santoni A, Polidori C, Mariani MP, Santoni G. Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression. Oncotarget 7: 43654-43668, (2016). 31. Wan J, Guo AA, Chowdhury I, Guo S, Hibbert J, Wang G, Liu M. TRPM7 Induces Mechanistic Target of Rap1b Through the Downregulation of miR-28-5p in Glioma Proliferation and Invasion. Front Oncol 9: 1413, (2019). 34. Tian Y, Yang T, Yu S, Liu C, He M, Hu C. Prostaglandin E2 increases migration and proliferation of human glioblastoma cells by activating transient receptor potential melastatin 7 channels. J Cell Mol Med 22: 6327-6337, (2018). 10. Bomben VC, Turner KL, Barclay TT, Sontheimer H. Transient receptor potential canonical channels are essential for chemotactic migration of human malignant gliomas. J Cell Physiol 226: 1879-1888, (2011). 25. Öztürk Y, Günaydın C, Yalçın F, Nazıroğlu M, Braidy N. Resveratrol Enhances Apoptotic and Oxidant Effects of Paclitaxel through TRPM2 Channel Activation in DBTRG Glioblastoma Cells. Oxid Med Cell Longev 2019: 4619865, (2019). 40. Wondergem R, Bartley JW. Menthol increases human glioblastoma intracellular Ca2+, BK channel activity and cell migration. J Biomed Sci 16: 90, (2009). 51. Ou-Yang Q, Li B, Xu M, Liang H. TRPV4 promotes the migration and invasion of glioma cells via AKT/Rac1 signaling. Biochem Biophys Res Commun 503: 876-881, (2018). 23. Chigurupati S, Venkataraman R, Barrera D, Naganathan A, Madan M, Paul L, Pattisapu JV, Kyriazis GA, Sugaya K, Bushnev S, Lathia JD, Rich JN, Chan SL. Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness. Cancer Res 70: 418-427, (2010). 47. Nabissi M, Morelli MB, Amantini C, Farfariello V, Ricci-Vitiani L, Caprodossi S, Arcella A, Santoni M, Giangaspero F, De Maria R, Santoni G. TRPV2 channel negatively controls glioma cell proliferation and resistance to Fas-induced apoptosis in ERK-dependent manner. Carcinogenesis 31: 794- 803, (2010). 30. Liu M, Inoue K, Leng T, Guo S, Xiong Z-g. TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways. Cell Signal 26: 2773-2781, (2014). 48. Nabissi M, Morelli MB, Santoni M, Santoni G. Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents. Carcinogenesis 34: 48-57, (2013). 8. Bomben VC, Sontheimer HW. Inhibition of transient receptor potential canonical channels impairs cytokinesis in human malignant gliomas. Cell Prolif 41: 98-121, (2008). 4. Prevarskaya N, Skryma R, Shuba Y. Ion channels and the hallmarks of cancer. Trends Mol Med 16: 107-121, (2010). 50. Morelli MB, Nabissi M, Amantini C, Farfariello V, Ricci-Vitiani L, di Martino S, Pallini R, Larocca LM, Caprodossi S, Santoni M, De Maria R, Santoni G. The transient receptor potential vanilloid-2 cation channel impairs glioblastoma stem-like cell proliferation and promotes differentiation. Int J Cancer 131: E1067-E1077, (2012). 28. Leng TD, Li MH, Shen JF, Liu ML, Li XB, Sun HW, Branigan D, Zeng Z, Si HF, Li J, Chen J, Xiong ZG. Suppression of TRPM7 inhibits proliferation, migration, and invasion of malignant human glioma cells. CNS Neurosci Ther 21: 252- 261, (2015). 12. Lepannetier S, Zanou N, Yerna X, Emeriau N, Dufour I, Masquelier J, Muccioli G, Tajeddine N, Gailly P. Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells. Cell calcium 60: 373-383, (2016). 27. Chen J, Dou Y, Zheng X, Leng T, Lu X, Ouyang Y, Sun H, Xing F, Mai J, Gu J, Lu B, Yan G, Lin J, Zhu W. TRPM7 channel inhibition mediates midazolam-induced proliferation loss in human malignant glioma. Tumour Biol 37: 14721-14731, (2016). 17. Chang HH, Cheng YC, Tsai WC, Tsao MJ, Chen Y. Pyr3 Induces Apoptosis and Inhibits Migration in Human Glioblastoma Cells. Cell Physiol Biochem 48: 1694-1702, (2018). 41. Liang W-Z, Chou C-T, Hsu S-S, Liao W-C, Shieh P, Kuo D-H, Tseng H-W, Kuo C-C, Jan C-R. The involvement of mitochondrial apoptotic pathway in eugenol-induced cell death in human glioblastoma cells. Toxicol Lett 232: 122-132, (2015). 22. Ding X, He Z, Zhou K, Cheng J, Yao H, Lu D, Cai R, Jin Y, Dong B, Xu Y, Wang Y. Essential role of TRPC6 channels in G2/M phase transition and development of human glioma. J Natl Cancer Inst 102: 1052-1068, (2010). 5. Morrone FB, Gehring MP, Nicoletti NF. Calcium Channels and Associated Receptors in Malignant Brain Tumor Therapy. Mol Pharmacol 90: 403-409, (2016). 49. Nabissi M, Morelli MB, Amantini C, Liberati S, Santoni M, Ricci-Vitiani L, Pallini R, Santoni G. Cannabidiol stimulates Aml-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2- dependent manner. Int J Cancer 137: 1855-1869, (2015). 1. Gallego O. Nonsurgical treatment of recurrent glioblastoma. Curr Oncol 22: e273-e281, (2015). 29. Chen W-L, Barszczyk A, Turlova E, Deurloo M, Liu B, Yang BB, Rutka JT, Feng Z-P, Sun H-S. Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion. Oncotarget 6: 16321-16340, (2015). 16. Uemura T, Green M, Warsh JJ. Chronic LiCl pretreatment suppresses thrombin-stimulated intracellular calcium mobilization through TRPC3 in astroglioma cells. Bipolar Disord 18: 549-562, (2016). 20. Richter JM, Schaefer M, Hill K. Clemizole hydrochloride is a novel and potent inhibitor of transient receptor potential channel TRPC5. Mol Pharmacol 86: 514-521, (2014). 26. Ertilav K, Nazıroğlu M, Ataizi ZS, Braidy N. Selenium Enhances the Apoptotic Efficacy of Docetaxel Through Activation of TRPM2 Channel in DBTRG Glioblastoma Cells. Neurotox Res 35: 797- 808, (2019). 35. Wong R, Turlova E, Feng ZP, Rutka JT, Sun HS. Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells. Oncotarget 8: 11239-11248, (2017). 38. Klumpp D, Frank SC, Klumpp L, Sezgin EC, Eckert M, Edalat L, Bastmeyer M, Zips D, Ruth P, Huber SM. TRPM8 is required for survival and radioresistance of glioblastoma cells. Oncotarget 8: 95896-95913, (2017). 39. Zeng J, Wu Y, Zhuang S, Qin L, Hua S, Mungur R, Pan J, Zhu Y, Zhan R. Identification of the role of TRPM8 in glioblastoma and its effect on proliferation, apoptosis and invasion of the U251 human glioblastoma cell line. Oncol Rep 42: 1517- 1526, (2019). 18. Barajas M, Andrade A, Hernandez-Hernandez O, Felix R, Arias-Montaño J-A. 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| References_xml | – reference: 23. Chigurupati S, Venkataraman R, Barrera D, Naganathan A, Madan M, Paul L, Pattisapu JV, Kyriazis GA, Sugaya K, Bushnev S, Lathia JD, Rich JN, Chan SL. Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness. Cancer Res 70: 418-427, (2010). – reference: 40. Wondergem R, Bartley JW. Menthol increases human glioblastoma intracellular Ca2+, BK channel activity and cell migration. J Biomed Sci 16: 90, (2009). – reference: 27. Chen J, Dou Y, Zheng X, Leng T, Lu X, Ouyang Y, Sun H, Xing F, Mai J, Gu J, Lu B, Yan G, Lin J, Zhu W. TRPM7 channel inhibition mediates midazolam-induced proliferation loss in human malignant glioma. Tumour Biol 37: 14721-14731, (2016). – reference: 5. Morrone FB, Gehring MP, Nicoletti NF. Calcium Channels and Associated Receptors in Malignant Brain Tumor Therapy. Mol Pharmacol 90: 403-409, (2016). – reference: 16. Uemura T, Green M, Warsh JJ. Chronic LiCl pretreatment suppresses thrombin-stimulated intracellular calcium mobilization through TRPC3 in astroglioma cells. Bipolar Disord 18: 549-562, (2016). – reference: 36. Sander P, Mostafa H, Soboh A, Schneider JM, Pala A, Baron A-K, Moepps B, Wirtz CR, Georgieff M, Schneider M. Vacquinol-1 inducible cell death in glioblastoma multiforme is counter regulated by TRPM7 activity induced by exogenous ATP. Oncotarget 8: 35124-35137, (2017). – reference: 12. Lepannetier S, Zanou N, Yerna X, Emeriau N, Dufour I, Masquelier J, Muccioli G, Tajeddine N, Gailly P. Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells. Cell calcium 60: 373-383, (2016). – reference: 34. Tian Y, Yang T, Yu S, Liu C, He M, Hu C. Prostaglandin E2 increases migration and proliferation of human glioblastoma cells by activating transient receptor potential melastatin 7 channels. J Cell Mol Med 22: 6327-6337, (2018). – reference: 3. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 100: 57-70, (2000). – reference: 30. Liu M, Inoue K, Leng T, Guo S, Xiong Z-g. TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways. Cell Signal 26: 2773-2781, (2014). – reference: 13. Xu J, Zhang Y, Guo X, Sun T. Glycogenolysis in Acquired Glioma Resistance to Temozolomide: A Role for the [Ca2+]i-dependent Activation of Na,KATPase/ERK1/2 Signaling. Front Pharmacol 9: 873, (2018). – reference: 28. Leng TD, Li MH, Shen JF, Liu ML, Li XB, Sun HW, Branigan D, Zeng Z, Si HF, Li J, Chen J, Xiong ZG. Suppression of TRPM7 inhibits proliferation, migration, and invasion of malignant human glioma cells. CNS Neurosci Ther 21: 252- 261, (2015). – reference: 8. Bomben VC, Sontheimer HW. Inhibition of transient receptor potential canonical channels impairs cytokinesis in human malignant gliomas. Cell Prolif 41: 98-121, (2008). – reference: 20. Richter JM, Schaefer M, Hill K. Clemizole hydrochloride is a novel and potent inhibitor of transient receptor potential channel TRPC5. Mol Pharmacol 86: 514-521, (2014). – reference: 24. Li S, Wang J, Wei Y, Liu Y, Ding X, Dong B, Xu Y, Wang Y. Crucial role of TRPC6 in maintaining the stability of HIF-1α in glioma cells under hypoxia. J Cell Sci 128: 3317-3329, (2015). – reference: 9. Bomben VC, Sontheimer H. Disruption of transient receptor potential canonical channel 1 causes incomplete cytokinesis and slows the growth of human malignant gliomas. Glia 58: 1145-1156, (2010). – reference: 52. Morelli MB, Amantini C, Tomassoni D, Nabissi M, Arcella A, Santoni G. Transient Receptor Potential Mucolipin-1 Channels in Glioblastoma: Role in Patient's Survival. Cancers (Basel) 11: 525, (2019). – reference: 6. Nilius B, Szallasi A. Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine. Pharmacol Rev 66: 676-814, (2014). – reference: 50. Morelli MB, Nabissi M, Amantini C, Farfariello V, Ricci-Vitiani L, di Martino S, Pallini R, Larocca LM, Caprodossi S, Santoni M, De Maria R, Santoni G. The transient receptor potential vanilloid-2 cation channel impairs glioblastoma stem-like cell proliferation and promotes differentiation. Int J Cancer 131: E1067-E1077, (2012). – reference: 42. Burke RC, Bardet SM, Carr L, Romanenko S, Arnaud-Cormos D, Leveque P, O'Connor RP. Nanosecond pulsed electric fields depolarize transmembrane potential via voltage-gated K+, Ca2+ and TRPM8 channels in U87 glioblastoma cells. Biochim Biophys Acta Biomembr 1859: 2040-2050, (2017). – reference: 22. Ding X, He Z, Zhou K, Cheng J, Yao H, Lu D, Cai R, Jin Y, Dong B, Xu Y, Wang Y. Essential role of TRPC6 channels in G2/M phase transition and development of human glioma. J Natl Cancer Inst 102: 1052-1068, (2010). – reference: 54. Deveci HA, Akyuva Y, Nur G, Nazıroğlu M. Alpha lipoic acid attenuates hypoxia-induced apoptosis, inflammation and mitochondrial oxidative stress via inhibition of TRPA1 channel in human glioblastoma cell line. Biomed Pharmacother 111: 292-304, (2019). – reference: 53. Morelli MB, Nabissi M, Amantini C, Tomassoni D, Rossi F, Cardinali C, Santoni M, Arcella A, Oliva MA, Santoni A, Polidori C, Mariani MP, Santoni G. Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression. Oncotarget 7: 43654-43668, (2016). – reference: 7. Alptekin M, Eroglu S, Tutar E, Sencan S, Geyik MA, Ulasli M, Demiryurek AT, Camci C. Gene expressions of TRP channels in glioblastoma multiforme and relation with survival. Tumour Biol 36: 9209-9213, (2015). – reference: 25. Öztürk Y, Günaydın C, Yalçın F, Nazıroğlu M, Braidy N. Resveratrol Enhances Apoptotic and Oxidant Effects of Paclitaxel through TRPM2 Channel Activation in DBTRG Glioblastoma Cells. Oxid Med Cell Longev 2019: 4619865, (2019). – reference: 38. Klumpp D, Frank SC, Klumpp L, Sezgin EC, Eckert M, Edalat L, Bastmeyer M, Zips D, Ruth P, Huber SM. TRPM8 is required for survival and radioresistance of glioblastoma cells. Oncotarget 8: 95896-95913, (2017). – reference: 17. Chang HH, Cheng YC, Tsai WC, Tsao MJ, Chen Y. Pyr3 Induces Apoptosis and Inhibits Migration in Human Glioblastoma Cells. Cell Physiol Biochem 48: 1694-1702, (2018). – reference: 51. Ou-Yang Q, Li B, Xu M, Liang H. TRPV4 promotes the migration and invasion of glioma cells via AKT/Rac1 signaling. Biochem Biophys Res Commun 503: 876-881, (2018). – reference: 48. Nabissi M, Morelli MB, Santoni M, Santoni G. Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents. Carcinogenesis 34: 48-57, (2013). – reference: 18. Barajas M, Andrade A, Hernandez-Hernandez O, Felix R, Arias-Montaño J-A. Histamine-induced Ca2+ entry in human astrocytoma U373 MG cells: evidence for involvement of store-operated channels. J Neurosci Res 86: 3456-3468, (2008). – reference: 29. Chen W-L, Barszczyk A, Turlova E, Deurloo M, Liu B, Yang BB, Rutka JT, Feng Z-P, Sun H-S. Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion. Oncotarget 6: 16321-16340, (2015). – reference: 19. Wei WC, Huang WC, Lin YP, Becker EBE, Ansorge O, Flockerzi V, Conti D, Cenacchi G, Glitsch MD. Functional expression of calciumpermeable canonical transient receptor potential 4-containing channels promotes migration of medulloblastoma cells. J Physiol 595: 5525-5544, (2017). – reference: 1. Gallego O. Nonsurgical treatment of recurrent glioblastoma. Curr Oncol 22: e273-e281, (2015). – reference: 43. Tominaga M, Caterina MJ. Thermosensation and pain. J Neurobiol 61: 3-12, (2004). – reference: 14. Wang B, Li W, Meng X, Zou F. 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| Title | Molecular basis of transient receptor potential channels in glioma |
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