Clinicoepidemiological Association between Carotid Atherosclerosis and Periodontal Disease

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Published inThe Japanese Journal of Conservative Dentistry Vol. 65; no. 3; pp. 189 - 197
Main Authors Toshiyuki, NAGASAWA, Mari, MORI, Yutaka, TERADA, Yasushi, FURUICHI, Tomofumi, KAWAKAMI
Format Journal Article
LanguageJapanese
Published The Japanese Society of Conservative Dentistry 30.06.2022
特定非営利活動法人 日本歯科保存学会
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ISSN0387-2343
2188-0808
DOI10.11471/shikahozon.65.189

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Author Yutaka, TERADA
Toshiyuki, NAGASAWA
Tomofumi, KAWAKAMI
Mari, MORI
Yasushi, FURUICHI
Author_FL 川上 智史
Yasushi FURUICHI
寺田 裕
Toshiyuki NAGASAWA
Mari MORI
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  organization: Division of Advanced Clinical Education, Department of Integrated Dental Education, School of Dentistry, Health Sciences University of Hokkaido
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  fullname: Mari, MORI
  organization: Division of General Dental Sciences, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido
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  organization: Division of General Dentistry, Health Sciences University of Hokkaido Hospital
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  organization: Division of General Dentistry, Health Sciences University of Hokkaido Hospital
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  fullname: Tomofumi, KAWAKAMI
  organization: Division of General Dental Sciences, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido
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References 9) 日本動脈硬化学会. 動脈硬化性疾患予防ガイドライン2017年版. 1版. 日本動脈硬化学会 : 東京 ; 2017. 19-22.
5) 日本動脈硬化学会. 動脈硬化性疾患予防のための脂質異常症診療ガイド2018年版. 1版. 日本動脈硬化学会 : 東京 ; 2018. 11-14, 148.
64) Wulandari EAT, Wijaya IP, Karim B, Ariyanto I, Tanudjaja SA, Lee S, Price P. Periodontitis and cytomegalovirus associate with atherosclerosis among HIV patients after 5 years on ART. J Acquir Immune Defic Syndr 2020; 85: 195-200.
24) Persson RE, Hollender LG, Powell VL, MacEntee M, Wyatt CC, Kiyak HA, Persson GR. Assessment of periodontal conditions and systemic disease in older subjects. Ⅱ. Focus on cardiovascular diseases. J Clin Periodontol 2002; 29: 803-810.
54) Tada S, Ikebe K, Kamide K, Gondo Y, Inomata C, Takeshita H, Matsuda KI, Kitamura M, Murakami S, Kabayama M, Oguro R, Nakama C, Kawai T, Yamamoto K, Sugimoto K, Shintani A, Ishihara T, Arai Y, Masui Y, Takahashi R, Rakugi H, Maeda Y. Relationship between atherosclerosis and occlusal support of natural teeth with mediating effect of atheroprotective nutrients: From the SONIC study. PLoS One 2017; 12: e0182563. doi : 10.1371/journal.pone.0182563
42) Zahnd G, Vray D, Serusclat A, Alibay D, Bartold M, Brown A, Durand M, Jamieson LM, Kapellas K, Maple-Brown LJ, O’Dea K, Moulin P, Celermajer DS, Skilton MR. Longitudinal displacement of the carotid wall and cardiovascular risk factors: associations with aging, adiposity, blood pressure and periodontal disease independent of cross-sectional distensibility and intima-media thickness. Ultrasound Med Biol 2012; 38: 1705-1715.
15) Nezu T, Hosomi N, Aoki S, Matsumoto M. Carotid intima-media thickness for atherosclerosis. J Atheroscler Thromb 2016; 23: 18-31.
22) Wang J, Geng X, Sun J, Zhang S, Yu W, Zhang X, Liu H. The risk of periodontitis for peripheral vascular disease: a systematic review. Rev Cardiovasc Med 2019; 20: 81-89.
6) 半田伸夫. 頸動脈エコーによる動脈硬化性病変評価のガイドライン (案). Neurosonology : 神経超音波医学 2002 ; 15 : 20-33.
20) Orlandi M, Suvan J, Petrie A, Donos N, Masi S, Hingorani A, Deanfield J, D’Aiuto F. Association between periodontal disease and its treatment, flow-mediated dilatation and carotid intima-media thickness: a systematic review and meta-analysis. Atherosclerosis 2014; 236: 39-46.
12) Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulation 1986; 74: 1399-1406.
57) Yamada S, Komiyama T, Ohi T, Murakami T, Miyoshi Y, Endo K, Hiratsuka T, Hara A, Satoh M, Tatsumi Y, Inoue R, Asayama K, Kikuya M, Hozawa A, Metoki H, Imai Y, Ohkubo T, Hattori Y. Regular dental visits, periodontitis, tooth loss, and atherosclerosis: The Ohasama study. J Periodontal Res 2022; 57: 615-622.
27) Engebretson SP, Lamster IB, Elkind MS, Rundek T, Serman NJ, Demmer RT, Sacco RL, Papapanou PN, Desvarieux M. Radiographic measures of chronic periodontitis and carotid artery plaque. Stroke 2005; 36: 561-566.
10) 日本脳神経超音波学会・栓子検出と治療学会合同ガイドライン作成委員会. 頸部血管超音波検査ガイドライン. Neurosonology : 神経超音波医学 2006 ; 19 : 49-69.
26) Desvarieux M, Schwahn C, Völzke H, Demmer RT, Lüdemann J, Kessler C, Jacobs DR Jr, John U, Kocher T. Gender differences in the relationship between periodontal disease, tooth loss, and atherosclerosis. Stroke 2004; 35: 2029-2035.
37) Ylöstalo P, Anttila S, Rajala U, Päivänsalo M, Keinänen-Kiukaanniemi S, Sakki T, Knuuttila M. Periodontal infection and subclinical atherosclerosis: the role of high-density lipoprotein as a modifying factor. J Clin Periodontol 2010; 37: 617-624.
68) Leite FRM, Nascimento GG, Peres KG, Demarco FF, Horta BL, Peres MA. Collider bias in the association of periodontitis and carotid intima-media thickness. Community Dent Oral Epidemiol 2020; 48: 264-270.
2) Vaizey JM, Clark-Kennedy AE. Dental sepsis: Anaemia, dyspepsia, and rheumatism. Br Med J 1939; 1: 1269-1273.
33) Söder B, Yakob M, Nowak J, Jogestrand T. Risk for the development of atherosclerosis in women with a high amount [corrected] of dental plaque and severe gingival inflammation. Int J Dent Hyg 2007; 5: 133-138. Erratum in: Int J Dent Hyg 2009; 7: 79. Nowak J [added]; Jogestrand T [added].
47) Wożakowska-Kapłon B, Włosowicz M, Gorczyca-Michta I, Górska R. Oral health status and the occurrence and clinical course of myocardial infarction in hospital phase: a case-control study. Cardiol J 2013; 20: 370-377.
29) Leivadaros E, van der Velden U, Bizzarro S, ten Heggeler JM, Gerdes VE, Hoek FJ, Nagy TO, Scholma J, Bakker SJ, Gans RO, ten Cate H, Loos BG. A pilot study into measurements of markers of atherosclerosis in periodontitis. J Periodontol 2005; 76: 121-128.
34) Cairo F, Castellani S, Gori AM, Nieri M, Baldelli G, Abbate R, Pini-Prato GP. Severe periodontitis in young adults is associated with sub-clinical atherosclerosis. J Clin Periodontol 2008; 35: 465-472.
18) Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation 2007; 115: 459-467.
36) Li X, Tse HF, Yiu KH, Jia N, Chen H, Li LS, Jin L. Increased levels of circulating endothelial progenitor cells in subjects with moderate to severe chronic periodontitis. J Clin Periodontol 2009; 36: 933-939.
7) 山崎和久, 高橋直紀, 五味一博. 第1部 臨床研究からのエビデンス 1) 歯周病と血管障害 概説. 日本歯周病学会. 歯周病と全身の健康. 1版. 医歯薬出版 : 東京 ; 2016. 10-11.
19) Kitamura A, Iso H, Imano H, Ohira T, Okada T, Sato S, Kiyama M, Tanigawa T, Yamagishi K, Shimamoto T. Carotid intima-media thickness and plaque characteristics as a risk factor for stroke in Japanese elderly men. Stroke 2004; 35: 2788-2794.
48) Ramesh A, Soroushian S, Ganguly R. Coincidence of calcified carotid atheromatous plaque, osteoporosis, and periodontal bone loss in dental panoramic radiographs. Imaging Sci Dent 2013; 43: 235-243.
3) Mattila KJ, Nieminen MS, Valtonen VV, Rasi VP, Kesäniemi YA, Syrjälä SL, Jungell PS, Isoluoma M, Hietaniemi K, Jokinen MJ. Association between dental health and acute myocardial infarction. BMJ 1989; 298: 779-781.
40) Li P, Zhang DK, Zhang JR, Chen L. Detection of the parameters for early atherosclerosis in patients with metabolic syndrome and periodontitis. Beijing Da Xue Xue Bao Yi Xue Ban/J Peking Univ Health Sci 2011; 43: 34-39. (in Chinese
16) O’Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med 1999; 340: 14-22.
13) Homma S, Hirose N, Ishida H, Ishii T, Araki G. Carotid plaque and intima-media thickness assessed by b-mode ultrasonography in subjects ranging from young adults to centenarians. Stroke 2001; 32: 830-835.
43) Franek E, Januszkiewicz-Caulier J, Błach A, Napora M, Jedynasty K, Budlewski T, Gozdowski D, Górska R. Intima-media thickness and other markers of atherosclerosis in patients with type 2 diabetes and periodontal disease. Kardiol Pol 2012; 70: 7-13.
65) Kitamura M, Ikebe K, Kamide K, Gondo Y, Yamashita M, Takedachi M, Nozaki T, Fujihara C, Yamada S, Kashiwagi Y, Miki K, Iwayama T, Hatta K, Mihara Y, Kurushima Y, Takeshita H, Kabayama M, Oguro R, Kawai T, Akasaka H, Takeya Y, Yamamoto K, Sugimoto K, Ishizaki T, Arai Y, Masui Y, Takahashi R, Rakugi H, Maeda Y, Murakami S. Association of periodontal disease with atherosclerosis in 70-year-old Japanese older adults. Odontology 2021; 109: 506-513.
32) Schillinger T, Kluger W, Exner M, Mlekusch W, Sabeti S, Amighi J, Wagner O, Minar E, Schillinger M. Dental and periodontal status and risk for progression of carotid atherosclerosis: the inflammation and carotid artery risk for atherosclerosis study dental substudy. Stroke 2006; 37: 2271-2276.
39) Vieira CL, Cury PR, Miname MH, Martinez LR, Bortolotto LA, Giuliano IB, Santos RD, Caramelli B. Severe periodontitis is associated with diastolic blood pressure elevation in individuals with heterozygous familial hypercholesterolemia: a pilot study. J Periodontol 2011; 82: 683-688.
25) Ravon NA, Hollender LG, McDonald V, Persson GR. Signs of carotid calcification from dental panoramic radiographs are in agreement with Doppler sonography results. J Clin Periodontol 2003; 30: 1084-1090.
62) Pussinen PJ, Paju S, Koponen J, Viikari JSA, Taittonen L, Laitinen T, Burgner DP, Kähönen M, Hutri-Kähönen N, Raitakari OT, Juonala M. Association of childhood oral infections with cardiovascular risk factors and subclinical atherosclerosis in adulthood. JAMA Netw Open 2019; 2: e192523. doi : 10.1001/jamanetworkopen.2019.2523
46) Hayashida H, Saito T, Kawasaki K, Kitamura M, Furugen R, Iwasaki T, Hayashida Y, Nakazato M, Sekita T, Takamura N, Maeda T. Association of periodontitis with carotid artery intima-media thickness and arterial stiffness in community-dwelling people in Japan: the Nagasaki Islands study. Atherosclerosis 2013; 229: 186-191.
1) Miller WD. The human mouth as a focus of infection. Lancet 1891; 138: 340-342.
45) Pinho MM, Faria-Almeida R, Azevedo E, Manso MC, Martins L. Periodontitis and atherosclerosis: an observational study. J Periodontal Res 2013; 48: 452-457.
17) del Sol AI, Moons KG, Hollander M, Hofman A, Koudstaal PJ, Grobbee DE, Breteler MM, Witteman JC, Bots ML. Is carotid intima-media thickness useful in cardiovascular disease risk assessment? The Rotterdam Study. Stroke 2001; 32: 1532-1538.
4) Syrjänen J, Peltola J, Valtonen V, Iivanainen M, Kaste M, Huttunen JK. Dental infections in association with cerebral infarction in young and middle-aged men. J Intern Med 1989; 225: 179-184.
51) Ahn YB, Shin MS, Han DH, Sukhbaatar M, Kim MS, Shin HS, Kim HD. Periodontitis is associated with the risk of subclinical atherosclerosis and peripheral arterial disease in Korean adults. Atherosclerosis 2016; 251: 311-318.
59) Desvarieux M, Demmer RT, Jacobs DR, Papapanou PN, Sacco RL, Rundek T. Changes in clinical and microbiological periodontal profiles relate to progression of carotid intima-media thickness: the Oral Infections and Vascular Disease Epidemiology study. J Am Heart Assoc 2013; 2: e000254. doi : 10.1161/JAH
References_xml – reference: 29) Leivadaros E, van der Velden U, Bizzarro S, ten Heggeler JM, Gerdes VE, Hoek FJ, Nagy TO, Scholma J, Bakker SJ, Gans RO, ten Cate H, Loos BG. A pilot study into measurements of markers of atherosclerosis in periodontitis. J Periodontol 2005; 76: 121-128.
– reference: 27) Engebretson SP, Lamster IB, Elkind MS, Rundek T, Serman NJ, Demmer RT, Sacco RL, Papapanou PN, Desvarieux M. Radiographic measures of chronic periodontitis and carotid artery plaque. Stroke 2005; 36: 561-566.
– reference: 1) Miller WD. The human mouth as a focus of infection. Lancet 1891; 138: 340-342.
– reference: 46) Hayashida H, Saito T, Kawasaki K, Kitamura M, Furugen R, Iwasaki T, Hayashida Y, Nakazato M, Sekita T, Takamura N, Maeda T. Association of periodontitis with carotid artery intima-media thickness and arterial stiffness in community-dwelling people in Japan: the Nagasaki Islands study. Atherosclerosis 2013; 229: 186-191.
– reference: 56) Shimizu Y, Yamanashi H, Kitamura M, Furugen R, Iwasaki T, Fukuda H, Hayashida H, Kawasaki K, Kiyoura K, Kawashiri SY, Saito T, Kawakami A, Maeda T. Association between human T cell leukemia virus type-1 (HTLV-1) infection and advanced periodontitis in relation to atherosclerosis among elderly Japanese: a cross-sectional study. Environ Health Prev Med 2019; 24: 81. doi : 10.1186/s12199-019-0836-2
– reference: 14) Barnett HJ, Taylor DW, Eliasziw M, Fox AJ, Ferguson GG, Haynes RB, Rankin RN, Clagett GP, Hachinski VC, Sackett DL, Thorpe KE, Meldrum HE, Spence JD. Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med 1998; 339: 1415-1425.
– reference: 28) Desvarieux M, Demmer RT, Rundek T, Boden-Albala B, Jacobs DR Jr, Sacco RL, Papapanou PN. Periodontal microbiota and carotid intima-media thickness: the Oral Infections and Vascular Disease Epidemiology Study (INVEST). Circulation 2005; 111: 576-582.
– reference: 21) Zeng XT, Leng WD, Lam YY, Yan BP, Wei XM, Weng H, Kwong JS. Periodontal disease and carotid atherosclerosis: A meta-analysis of 17,330 participants. Int J Cardiol 2016; 203: 1044-1051.
– reference: 53) Gerhard-Herman MD, Gornik HL, Barrett C, Barshes NR, Corriere MA, Drachman DE, Fleisher LA, Fowkes FGR, Hamburg NM, Kinlay S, Lookstein R, Misra S, Mureebe L, Olin JW, Patel RAG, Regensteiner JG, Schanzer A, Shishehbor MH, Stewart KJ, Treat-Jacobson D, Walsh E. 2016 AHA/ACC guideline on the management of patients with lower extremity peripheral artery disease: a report of the American college of cardiology/American heart association task force on clinical practice guidelines. J Am Coll Cardiol 2017; 69: e71-e126. doi : 10.1016/j.jace.2016.11.007. Erratum in: J Am Coll Cardiol 2017; 69: 1521.
– reference: 44) Puhar I, Lovrencic-Huzjan A, Sodec-Simicevic D, Strineka M, Bozic D, Plancak D. Carotid intima-media thickness in patients with chronic and aggressive periodontitis. Deblijina intime-medije karotidnih arterija kod pacijenata s kronicnim i agresivnim parodontitisom. Acta Stomatol Croat 2012; 46: 255-262. (in Croatian, English)
– reference: 24) Persson RE, Hollender LG, Powell VL, MacEntee M, Wyatt CC, Kiyak HA, Persson GR. Assessment of periodontal conditions and systemic disease in older subjects. Ⅱ. Focus on cardiovascular diseases. J Clin Periodontol 2002; 29: 803-810.
– reference: 62) Pussinen PJ, Paju S, Koponen J, Viikari JSA, Taittonen L, Laitinen T, Burgner DP, Kähönen M, Hutri-Kähönen N, Raitakari OT, Juonala M. Association of childhood oral infections with cardiovascular risk factors and subclinical atherosclerosis in adulthood. JAMA Netw Open 2019; 2: e192523. doi : 10.1001/jamanetworkopen.2019.2523
– reference: 7) 山崎和久, 高橋直紀, 五味一博. 第1部 臨床研究からのエビデンス 1) 歯周病と血管障害 概説. 日本歯周病学会. 歯周病と全身の健康. 1版. 医歯薬出版 : 東京 ; 2016. 10-11.
– reference: 17) del Sol AI, Moons KG, Hollander M, Hofman A, Koudstaal PJ, Grobbee DE, Breteler MM, Witteman JC, Bots ML. Is carotid intima-media thickness useful in cardiovascular disease risk assessment? The Rotterdam Study. Stroke 2001; 32: 1532-1538.
– reference: 37) Ylöstalo P, Anttila S, Rajala U, Päivänsalo M, Keinänen-Kiukaanniemi S, Sakki T, Knuuttila M. Periodontal infection and subclinical atherosclerosis: the role of high-density lipoprotein as a modifying factor. J Clin Periodontol 2010; 37: 617-624.
– reference: 19) Kitamura A, Iso H, Imano H, Ohira T, Okada T, Sato S, Kiyama M, Tanigawa T, Yamagishi K, Shimamoto T. Carotid intima-media thickness and plaque characteristics as a risk factor for stroke in Japanese elderly men. Stroke 2004; 35: 2788-2794.
– reference: 41) Lopez-Jornet P, Berna-Mestre JD, Berna-Serna JD, Camacho-Alonso F, Fernandez-Millan S, Reus-Pintado M. Measurement of atherosclerosis markers in patients with periodontitis: a case-control study. J Periodontol 2012; 83: 690-698.
– reference: 35) Piconi S, Trabattoni D, Luraghi C, Perilli E, Borelli M, Pacei M, Rizzardini G, Lattuada A, Bray DH, Catalano M, Sparaco A, Clerici M. Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima-media thickness. FASEB J 2009; 23: 1196-1204.
– reference: 47) Wożakowska-Kapłon B, Włosowicz M, Gorczyca-Michta I, Górska R. Oral health status and the occurrence and clinical course of myocardial infarction in hospital phase: a case-control study. Cardiol J 2013; 20: 370-377.
– reference: 51) Ahn YB, Shin MS, Han DH, Sukhbaatar M, Kim MS, Shin HS, Kim HD. Periodontitis is associated with the risk of subclinical atherosclerosis and peripheral arterial disease in Korean adults. Atherosclerosis 2016; 251: 311-318.
– reference: 45) Pinho MM, Faria-Almeida R, Azevedo E, Manso MC, Martins L. Periodontitis and atherosclerosis: an observational study. J Periodontal Res 2013; 48: 452-457.
– reference: 9) 日本動脈硬化学会. 動脈硬化性疾患予防ガイドライン2017年版. 1版. 日本動脈硬化学会 : 東京 ; 2017. 19-22.
– reference: 54) Tada S, Ikebe K, Kamide K, Gondo Y, Inomata C, Takeshita H, Matsuda KI, Kitamura M, Murakami S, Kabayama M, Oguro R, Nakama C, Kawai T, Yamamoto K, Sugimoto K, Shintani A, Ishihara T, Arai Y, Masui Y, Takahashi R, Rakugi H, Maeda Y. Relationship between atherosclerosis and occlusal support of natural teeth with mediating effect of atheroprotective nutrients: From the SONIC study. PLoS One 2017; 12: e0182563. doi : 10.1371/journal.pone.0182563
– reference: 15) Nezu T, Hosomi N, Aoki S, Matsumoto M. Carotid intima-media thickness for atherosclerosis. J Atheroscler Thromb 2016; 23: 18-31.
– reference: 31) Franek E, Blaschyk R, Kolonko A, Mazur-Psonka L, Łangowska-Adamczyk H, Kokot F, Wiecek A. Chronic periodontitis in hemodialysis patients with chronic kidney disease is associated with elevated serum C-reactive protein concentration and greater intima-media thickness of the carotid artery. J Nephrol 2006; 19: 346-351.
– reference: 42) Zahnd G, Vray D, Serusclat A, Alibay D, Bartold M, Brown A, Durand M, Jamieson LM, Kapellas K, Maple-Brown LJ, O’Dea K, Moulin P, Celermajer DS, Skilton MR. Longitudinal displacement of the carotid wall and cardiovascular risk factors: associations with aging, adiposity, blood pressure and periodontal disease independent of cross-sectional distensibility and intima-media thickness. Ultrasound Med Biol 2012; 38: 1705-1715.
– reference: 38) Carallo C, Fortunato L, de Franceschi MS, Irace C, Tripolino C, Cristofaro MG, Giudice M, Gnasso A. Periodontal disease and carotid atherosclerosis: are hemodynamic forces a link?. Atherosclerosis 2010; 213: 263-267.
– reference: 12) Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulation 1986; 74: 1399-1406.
– reference: 64) Wulandari EAT, Wijaya IP, Karim B, Ariyanto I, Tanudjaja SA, Lee S, Price P. Periodontitis and cytomegalovirus associate with atherosclerosis among HIV patients after 5 years on ART. J Acquir Immune Defic Syndr 2020; 85: 195-200.
– reference: 8) Ross R. Atherosclerosis―an inflammatory disease. N Engl J Med 1999; 340: 115-126.
– reference: 48) Ramesh A, Soroushian S, Ganguly R. Coincidence of calcified carotid atheromatous plaque, osteoporosis, and periodontal bone loss in dental panoramic radiographs. Imaging Sci Dent 2013; 43: 235-243.
– reference: 20) Orlandi M, Suvan J, Petrie A, Donos N, Masi S, Hingorani A, Deanfield J, D’Aiuto F. Association between periodontal disease and its treatment, flow-mediated dilatation and carotid intima-media thickness: a systematic review and meta-analysis. Atherosclerosis 2014; 236: 39-46.
– reference: 25) Ravon NA, Hollender LG, McDonald V, Persson GR. Signs of carotid calcification from dental panoramic radiographs are in agreement with Doppler sonography results. J Clin Periodontol 2003; 30: 1084-1090.
– reference: 34) Cairo F, Castellani S, Gori AM, Nieri M, Baldelli G, Abbate R, Pini-Prato GP. Severe periodontitis in young adults is associated with sub-clinical atherosclerosis. J Clin Periodontol 2008; 35: 465-472.
– reference: 58) Vernon LT, Babineau DC, Demko CA, Lederman MM, Wang X, Toossi Z, Weinberg A, Rodriguez B. A prospective cohort study of periodontal disease measures and cardiovascular disease markers in HIV-infected adults. AIDS Res Hum Retroviruses 2011; 27: 1157-1166.
– reference: 23) Beck JD, Elter JR, Heiss G, Couper D, Mauriello SM, Offenbacher S. Relationship of periodontal disease to carotid artery intima-media wall thickness: the atherosclerosis risk in communities (ARIC) study. Arterioscler Thromb Vasc Biol 2001; 21: 1816-1822.
– reference: 39) Vieira CL, Cury PR, Miname MH, Martinez LR, Bortolotto LA, Giuliano IB, Santos RD, Caramelli B. Severe periodontitis is associated with diastolic blood pressure elevation in individuals with heterozygous familial hypercholesterolemia: a pilot study. J Periodontol 2011; 82: 683-688.
– reference: 68) Leite FRM, Nascimento GG, Peres KG, Demarco FF, Horta BL, Peres MA. Collider bias in the association of periodontitis and carotid intima-media thickness. Community Dent Oral Epidemiol 2020; 48: 264-270.
– reference: 57) Yamada S, Komiyama T, Ohi T, Murakami T, Miyoshi Y, Endo K, Hiratsuka T, Hara A, Satoh M, Tatsumi Y, Inoue R, Asayama K, Kikuya M, Hozawa A, Metoki H, Imai Y, Ohkubo T, Hattori Y. Regular dental visits, periodontitis, tooth loss, and atherosclerosis: The Ohasama study. J Periodontal Res 2022; 57: 615-622.
– reference: 50) Yu H, Qi LT, Liu LS, Wang XY, Zhang Y, Huo Y, Luan QX. Association of carotid intima-media thickness and atherosclerotic plaque with periodontal status. J Dent Res 2014; 93: 744-751.
– reference: 13) Homma S, Hirose N, Ishida H, Ishii T, Araki G. Carotid plaque and intima-media thickness assessed by b-mode ultrasonography in subjects ranging from young adults to centenarians. Stroke 2001; 32: 830-835.
– reference: 10) 日本脳神経超音波学会・栓子検出と治療学会合同ガイドライン作成委員会. 頸部血管超音波検査ガイドライン. Neurosonology : 神経超音波医学 2006 ; 19 : 49-69.
– reference: 63) Tong C, Wang YH, Chang YC. Increased risk of carotid atherosclerosis in male patients with chronic periodontitis: A nationwide population-based retrospective cohort study. Int J Environ Res Public Health 2019; 16: 2635. doi : 10.3390/ijerph16152635
– reference: 65) Kitamura M, Ikebe K, Kamide K, Gondo Y, Yamashita M, Takedachi M, Nozaki T, Fujihara C, Yamada S, Kashiwagi Y, Miki K, Iwayama T, Hatta K, Mihara Y, Kurushima Y, Takeshita H, Kabayama M, Oguro R, Kawai T, Akasaka H, Takeya Y, Yamamoto K, Sugimoto K, Ishizaki T, Arai Y, Masui Y, Takahashi R, Rakugi H, Maeda Y, Murakami S. Association of periodontal disease with atherosclerosis in 70-year-old Japanese older adults. Odontology 2021; 109: 506-513.
– reference: 5) 日本動脈硬化学会. 動脈硬化性疾患予防のための脂質異常症診療ガイド2018年版. 1版. 日本動脈硬化学会 : 東京 ; 2018. 11-14, 148.
– reference: 40) Li P, Zhang DK, Zhang JR, Chen L. Detection of the parameters for early atherosclerosis in patients with metabolic syndrome and periodontitis. Beijing Da Xue Xue Bao Yi Xue Ban/J Peking Univ Health Sci 2011; 43: 34-39. (in Chinese)
– reference: 61) Kudo C, Shin WS, Sasaki N, Harai K, Kato K, Seino H, Goke E, Fujino T, Kuribayashi N, Pearce YO, Taira M, Matsushima R, Minabe M, Takashiba S; Periodontitis and Atherosclerosis Project-Tokyo and Chiba Consortiums. Effects of periodontal treatment on carotid intima-media thickness in patients with lifestyle-related diseases: Japanese prospective multicentre observational study. Odontology 2018; 106: 316-327. Erratum in: Odontology 2018; 106: 349.
– reference: 11) 日本超音波医学会用語・診断基準委員会, 頸動脈超音波診断ガイドライン小委員会. 超音波による頸動脈病変の標準的評価法2017 (2018年1月29日公示). https://www.jsum.or.jp/committee/diagnostic/pdf/jsum0515_guideline.pdf (2022年3月26日アクセス)
– reference: 33) Söder B, Yakob M, Nowak J, Jogestrand T. Risk for the development of atherosclerosis in women with a high amount [corrected] of dental plaque and severe gingival inflammation. Int J Dent Hyg 2007; 5: 133-138. Erratum in: Int J Dent Hyg 2009; 7: 79. Nowak J [added]; Jogestrand T [added].
– reference: 30) Söder PO, Söder B, Nowak J, Jogestrand T. Early carotid atherosclerosis in subjects with periodontal diseases. Stroke 2005; 36: 1195-1200.
– reference: 4) Syrjänen J, Peltola J, Valtonen V, Iivanainen M, Kaste M, Huttunen JK. Dental infections in association with cerebral infarction in young and middle-aged men. J Intern Med 1989; 225: 179-184.
– reference: 59) Desvarieux M, Demmer RT, Jacobs DR, Papapanou PN, Sacco RL, Rundek T. Changes in clinical and microbiological periodontal profiles relate to progression of carotid intima-media thickness: the Oral Infections and Vascular Disease Epidemiology study. J Am Heart Assoc 2013; 2: e000254. doi : 10.1161/JAHA.113.000254
– reference: 3) Mattila KJ, Nieminen MS, Valtonen VV, Rasi VP, Kesäniemi YA, Syrjälä SL, Jungell PS, Isoluoma M, Hietaniemi K, Jokinen MJ. Association between dental health and acute myocardial infarction. BMJ 1989; 298: 779-781.
– reference: 66) Kapellas K, Maple-Brown LJ, Jamieson LM, Do LG, O’Dea K, Brown A, Cai TY, Anstey NM, Sullivan DR, Wang H, Celermajer DS, Slade GD, Skilton MR. Effect of periodontal therapy on arterial structure and function among Aboriginal Australians: a randomized, controlled trial. Hypertension 2014; 64: 702-708.
– reference: 55) 寺田 裕, 長澤敏行, 小西ゆみ子, 尾立達治, 森 真理, 舞田健夫, 森谷 満, 井出 肇, 辻 昌宏, 川上智史, 古市保志. 脂質異常症患者における残存歯数および重度歯周炎と頸動脈内中膜厚との関連性. 日歯保存誌 2018 ; 61 : 132-144.
– reference: 43) Franek E, Januszkiewicz-Caulier J, Błach A, Napora M, Jedynasty K, Budlewski T, Gozdowski D, Górska R. Intima-media thickness and other markers of atherosclerosis in patients with type 2 diabetes and periodontal disease. Kardiol Pol 2012; 70: 7-13.
– reference: 18) Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation 2007; 115: 459-467.
– reference: 2) Vaizey JM, Clark-Kennedy AE. Dental sepsis: Anaemia, dyspepsia, and rheumatism. Br Med J 1939; 1: 1269-1273.
– reference: 36) Li X, Tse HF, Yiu KH, Jia N, Chen H, Li LS, Jin L. Increased levels of circulating endothelial progenitor cells in subjects with moderate to severe chronic periodontitis. J Clin Periodontol 2009; 36: 933-939.
– reference: 32) Schillinger T, Kluger W, Exner M, Mlekusch W, Sabeti S, Amighi J, Wagner O, Minar E, Schillinger M. Dental and periodontal status and risk for progression of carotid atherosclerosis: the inflammation and carotid artery risk for atherosclerosis study dental substudy. Stroke 2006; 37: 2271-2276.
– reference: 16) O’Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med 1999; 340: 14-22.
– reference: 6) 半田伸夫. 頸動脈エコーによる動脈硬化性病変評価のガイドライン (案). Neurosonology : 神経超音波医学 2002 ; 15 : 20-33.
– reference: 26) Desvarieux M, Schwahn C, Völzke H, Demmer RT, Lüdemann J, Kessler C, Jacobs DR Jr, John U, Kocher T. Gender differences in the relationship between periodontal disease, tooth loss, and atherosclerosis. Stroke 2004; 35: 2029-2035.
– reference: 52) Criqui MH, Aboyans V. Epidemiology of peripheral artery disease. Circ Res 2015; 24: 116: 1509-1526. Erratum in: Circ Res 2015; 19: 117: e12.
– reference: 22) Wang J, Geng X, Sun J, Zhang S, Yu W, Zhang X, Liu H. The risk of periodontitis for peripheral vascular disease: a systematic review. Rev Cardiovasc Med 2019; 20: 81-89.
– reference: 67) Toregeani JF, Nassar CA, Nassar PO, Toregeani KM, Gonzatto GK, Vendrame R, Castilhos JS, Rotta LS, Reinheimer AC, Longoni A, Barcella MW. Evaluation of periodontitis treatment effects on carotid intima-media thickness and expression of laboratory markers related to atherosclerosis. Gen Dent 2016; 64: 55-62.
– reference: 60) Napora M, Grabowska E, Górska R. Prospective analysis of the relationship between the state of periodontal tissues and changes in selected cardiovascular parameters in patients with type 2 diabetes. Adv Clin Exp Med 2016; 25: 879-886.
– reference: 49) Jung YS, Shin MH, Kim IS, Kweon SS, Lee YH, Kim OJ, Kim YJ, Chung HJ, Kim OS. Relationship between periodontal disease and subclinical atherosclerosis: the Dong-gu study. J Clin Periodontol 2014; 41: 262-268.
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SubjectTerms 歯周病
疫学
頸動脈内中膜厚
頸動脈硬化
Title Clinicoepidemiological Association between Carotid Atherosclerosis and Periodontal Disease
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