A case of severe hypothermia with acute suppurative cholangitis resulting in bradycardia and cardiac arrest during rewarming

A 74-year-old man with severe hypothermia complicated by septic shock due to acute suppurative cholangitis was admitted to our hospital in an unconscious state. On admission, his rectal temperature was 26.7 ℃, systolic blood pressure was 57 mmHg and ECG showed sinus bradycardia at 49 beats/min. Larg...

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Published inKANTO Journal of Japanese Association for Acute Medicine Vol. 43; no. 4; pp. 224 - 227
Main Authors Ikeda, Mayuko, Hirose, Yosuke, Yuzawa, Hiroko, Kondo, Kengo, Hosono, Kazuki, Sadahiro, Tomohito
Format Journal Article
LanguageJapanese
Published Japanese Association for Acute Medicine of Kanto 28.12.2022
日本救急医学会関東地方会
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Abstract A 74-year-old man with severe hypothermia complicated by septic shock due to acute suppurative cholangitis was admitted to our hospital in an unconscious state. On admission, his rectal temperature was 26.7 ℃, systolic blood pressure was 57 mmHg and ECG showed sinus bradycardia at 49 beats/min. Large volumes of warm intravenous fluid were administered, but the patient went into cardiac arrest twice during warming. Cardiopulmonary resuscitation was promptly performed, and spontaneous circulation was restored twice. Hypothermia, especially in the elderly, should be treated urgently by suspecting infection and investigating the cause as well as restoring body temperature. In addition, during the treatment of hypothermia, it is necessary to keep in mind that not only VT/VF but also cardiac arrest may occur during warming.
AbstractList A 74-year-old man with severe hypothermia complicated by septic shock due to acute suppurative cholangitis was admitted to our hospital in an unconscious state. On admission, his rectal temperature was 26.7 ℃, systolic blood pressure was 57 mmHg and ECG showed sinus bradycardia at 49 beats/min. Large volumes of warm intravenous fluid were administered, but the patient went into cardiac arrest twice during warming. Cardiopulmonary resuscitation was promptly performed, and spontaneous circulation was restored twice. Hypothermia, especially in the elderly, should be treated urgently by suspecting infection and investigating the cause as well as restoring body temperature. In addition, during the treatment of hypothermia, it is necessary to keep in mind that not only VT/VF but also cardiac arrest may occur during warming.
A 74-year-old man with severe hypothermia complicated by septic shock due to acute suppurative cholangitis was admitted to our hospital in an unconscious state. On admission, his rectal temperature was 26.7 ℃, systolic blood pressure was 57 mmHg and ECG showed sinus bradycardia at 49 beats/min. Large volumes of warm intravenous fluid were administered, but the patient went into cardiac arrest twice during warming. Cardiopulmonary resuscitation was promptly performed, and spontaneous circulation was restored twice. Hypothermia, especially in the elderly, should be treated urgently by suspecting infection and investigating the cause as well as restoring body temperature. In addition, during the treatment of hypothermia, it is necessary to keep in mind that not only VT/VF but also cardiac arrest may occur during warming. 74歳男性が意識障害と直腸温26.7℃の高度低体温で搬送された。意識レベルはGCSでE4V1M4。血圧57/31mmHg。心電図では49/分の洞性徐脈がみられた。初療室で加温輸液を約2時間で2,500mL急速投与したが, 徐脈を経て心静止した。速やかに心肺蘇生法 (cardiopulmonary resuscitation ; CPR) を施行し自己心拍は再開し, その後, 加温輸液とブランケットによる復温を継続した。また, カテコラミンの持続投与も行っていたが血圧への反応は乏しく, 再び徐脈から心静止へ移行したが, 再度CPRを施行し自己心拍は再開した。腹部CT検査で急性化膿性胆管炎の所見がみられ, 敗血症性ショックの併発が示唆され, 直ちに広域抗菌薬による治療を開始し, 翌日には覚醒が得られた。低体温症はとくに高齢者では感染症を疑い, 復温と同時に原因検索とその治療を迅速に行うべきである。また, 低体温症例の復温中は心室頻拍/心室細動だけでなく, 心静止となることも念頭に置き治療を行う必要がある。
Author Sadahiro, Tomohito
Hirose, Yosuke
Kondo, Kengo
Ikeda, Mayuko
Yuzawa, Hiroko
Hosono, Kazuki
Author_FL 池田 万優子
貞広 智仁
細野 一樹
廣瀬 陽介
近藤 乾伍
湯澤 紘子
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  fullname: 近藤 乾伍
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  fullname: Ikeda, Mayuko
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  fullname: Sadahiro, Tomohito
  organization: Tokyo Women's Medical University Yachiyo Medical Center, Emergency and Critical Care Medicine
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DocumentTitleAlternate 高度低体温症で来院し, 復温の過程で徐脈から心静止に至った急性化膿性胆管炎の1例
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References 1) Frei C, Darocha T, Debaty G, et al : Clinical characteristics and outcomes of witnessed hypothermic cardiac arrest : A systematic review on rescue collapse. Resuscitation 2019 ; 137 : 41-48.
2) Kramer MR, Vandijk J, Rosin AJ : Mortality in elderly patients with thermoregulatory failure. Arch Intern Med 1989 ; 149 : 1521-1523.
4) 中野忠澄, 井藤秀喜, 稲松孝思, 他 : 老年者低体温症例の検討. 日老医誌 1985 ; 22 : 228-233.
3) Darowski A, Najim Z, Weinberg JR, et al : Hypothermia and infection in elderly patients admitted to hospital. Age Ageing 1991 ; 20 : 100-106.
References_xml – reference: 2) Kramer MR, Vandijk J, Rosin AJ : Mortality in elderly patients with thermoregulatory failure. Arch Intern Med 1989 ; 149 : 1521-1523.
– reference: 3) Darowski A, Najim Z, Weinberg JR, et al : Hypothermia and infection in elderly patients admitted to hospital. Age Ageing 1991 ; 20 : 100-106.
– reference: 4) 中野忠澄, 井藤秀喜, 稲松孝思, 他 : 老年者低体温症例の検討. 日老医誌 1985 ; 22 : 228-233.
– reference: 1) Frei C, Darocha T, Debaty G, et al : Clinical characteristics and outcomes of witnessed hypothermic cardiac arrest : A systematic review on rescue collapse. Resuscitation 2019 ; 137 : 41-48.
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Snippet A 74-year-old man with severe hypothermia complicated by septic shock due to acute suppurative cholangitis was admitted to our hospital in an unconscious...
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SubjectTerms accidental hypothermia
cardiac arrest
septic shock
偶発性低体温症
心停止
敗血症性ショック
Title A case of severe hypothermia with acute suppurative cholangitis resulting in bradycardia and cardiac arrest during rewarming
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