リポソームによる抗癌剤の抗腫瘍効果の最適化に関する速度論的研究 生理学的モデルに基づいたシミュレーションスタディ
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| Published in | Drug Delivery System Vol. 12; no. 6; pp. 403 - 408 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
日本DDS学会
10.11.1997
|
| Online Access | Get full text |
| ISSN | 0913-5006 1881-2732 |
| DOI | 10.2745/dds.12.403 |
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| Author | 飯田, 慎也 永易, 篤 原島, 秀吉 浦上, 裕美子 際田, 弘志 |
|---|---|
| Author_xml | – sequence: 1 fullname: 浦上, 裕美子 organization: 徳島大学薬学都薬剤学教室 – sequence: 1 fullname: 飯田, 慎也 organization: 徳島大学薬学都薬剤学教室 – sequence: 1 fullname: 永易, 篤 organization: 徳島大学薬学都薬剤学教室 – sequence: 1 fullname: 際田, 弘志 organization: 徳島大学薬学都薬剤学教室 – sequence: 1 fullname: 原島, 秀吉 organization: 徳島大学薬学都薬剤学教室 |
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| References | 20) Hori K, Zhang Qui-H, Saito S, Tanda S, Li Hao-C, Suzuki M : Microvascular mechanisms of change in tumor blood flow elicited by vasopressors. Jpn. J. Cancer Chemother. 21 : 403-408, 1994. 17) Horoqitz AT, Barenholz Y, Gabizon AA : In vitro cytotoxicity of liposome-encapsulated doxorubicin : dependence on liposome composition and drug release. Biochim. Biophys. Acta 1109 : 203-209, 1992. 5) Fischl MA, Krown SE, O'Boyle KP, Mitsuyasu R, Miles S, Wernz JC, Volberding PA, Kahn J, Groopman JE, Feinberg J, Woody M, the AIDS Clinical Trials Group : Weekly doxorubicin in the treatment of patients with AIDS-related Kaposi's sarcoma. J. Acquir. Immune Defic. Syndr. 6 : 259-264, 1993. 7) Bjorkman S, Stanski DR, Verotta D, Harashima H : Comparative tissue concentration profile of fentanyl and alfentanil in humans predicted from tissue/blood partition data obtained in rats. Anesthesiology 72 : 865-873, 1990. 9) Ozawa S, Sugiyama Y, Mitsuhashi Y, Kobayashi T, Inaba M : Cell killing action of cell cycle phase-non-specific antitumor agents is dependent on concentration-time product. Cancer Chemother. Pharmacol. 21 : 185-190, 1988. 4) Vaage J, Mayhew E, Lasic D, Martin F : Therapy of primary and metastatic mouse mammary carcinomas with doxorubicin encapsulated in long circulating liposomes. Int. J. Cancer 51 : 942-948, 1992. 14) Yamaoka K, Nakagawa TA : Nonlinear least squares program based on differential equations, MULTI (RUNGE), for microcomputers. J. Pharmacobio. Dyn. 6 : 595-606, 1983. 1) Woodle MC, Lasic DD : Sterically stabilized liposomes. Biochim. Biophys. Acta 1113 : 171-199, 1992. 3) Huang SK, Mayhew R, Gilani S, Lasic DD, Martin FJ, Papahadjopoulos D : Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon carcinoma. Cancer Res. 52 : 6774-6781, 1992. 10) Huang SK, Lee K-D, Hong K, Friend DS, Papahadjopoulos D : Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice. Cancer Res. 52 : 5135-5143, 1992. 15) Uchiyama K, Nagayasu A, Yamagiwa Y, Nishida T, Harashima H, Kiwada H : Effects of the size and fluidity of liposomes on their accumulation in tumors : A presumption of their interaction with tumors. Int. J. Pharm. 121 : 195-203, 1995. 18) Mayhew EG, Goldrosen MH, Vaage J, Rustum YM : Effect of liposome-entrapped doxorubicin on liver metastases of mouse colon carcinomas 26 and 38. J. Natl. Cancer Inst. 78 : 707-713, 1987. 2) Papahadjopoulos D, Allen TM, Gabizon A, Mayhew E, Matthay K, Huang SK, Lee K-D, Woodle MC, Lasic DD, Redemann C, Martin FJ : Sterically stabilized liposomes : Improvements in pharmacokinetics and antitumor therapeutic efficacy. Proc. Natl. Acad. Sci. USA 88 : 11460-11464, 1991. 16) Milano G, Cassuto-Viguier E, Fischel JL, Formento P, Renee N, Frenay M, Thyss A, Namer M : Doxorubicin weekly low dose administration : in vitro cytotoxicity generated by the typical pharmacokinetic profile. Eur. J. Cancer 28A : 1881-1885, 1992. 6) Sawada Y, Harashima H, Hanano M, Sugiyama Y, Iga T : Prediction of the plasma concentration time courses of various drugs in humans based on data from rats. J. Pharmacobio. Dyn. 8 : 757-766, 1985. 8) Wada DR, Harashima H, Ebling WF, Osaki EW, Stanski DR : Effects of thiopental on regional blood flows in the rat. Anesthesiology 84 : 596-604, 1996. 19) Eskey CJ, Wolmark N, McDowell CL, Domach MM, Jain RK : Residence time distributions of various tracers in tumors : Implications for drug delivery and blood flow measurement. J. Natl. Cancer Inst. 86 : 293-299, 1994. 11) Rahman A, Carmichael D, Harris M, Roh JK : Comparative pharmacokinetics of free doxorubicin and doxorubicin entrapped in cardiolipin liposomes. Cancer Res. 46 : 2295-2299, 1986. 12) Yamaoka K, Tanigawara Y, Nakagawa T, Uno TA : Pharmacokinetic analysis program (MULTI) for microcomputer, J. Pharmacobio. Dyn. 4 : 879-890, 1981. 13) Mayer LD, Bally MB, Cullis PR, Wilson SL, Emerman JT : Comparison of free and liposome encapsulated doxorubicin tumor drug uptake and antitumor efficacy in the SC115 murine mamary tumor. Cancer Let. 53 : 183-190, 1990. |
| References_xml | – reference: 18) Mayhew EG, Goldrosen MH, Vaage J, Rustum YM : Effect of liposome-entrapped doxorubicin on liver metastases of mouse colon carcinomas 26 and 38. J. Natl. Cancer Inst. 78 : 707-713, 1987. – reference: 4) Vaage J, Mayhew E, Lasic D, Martin F : Therapy of primary and metastatic mouse mammary carcinomas with doxorubicin encapsulated in long circulating liposomes. Int. J. Cancer 51 : 942-948, 1992. – reference: 9) Ozawa S, Sugiyama Y, Mitsuhashi Y, Kobayashi T, Inaba M : Cell killing action of cell cycle phase-non-specific antitumor agents is dependent on concentration-time product. Cancer Chemother. Pharmacol. 21 : 185-190, 1988. – reference: 10) Huang SK, Lee K-D, Hong K, Friend DS, Papahadjopoulos D : Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice. Cancer Res. 52 : 5135-5143, 1992. – reference: 17) Horoqitz AT, Barenholz Y, Gabizon AA : In vitro cytotoxicity of liposome-encapsulated doxorubicin : dependence on liposome composition and drug release. Biochim. Biophys. Acta 1109 : 203-209, 1992. – reference: 19) Eskey CJ, Wolmark N, McDowell CL, Domach MM, Jain RK : Residence time distributions of various tracers in tumors : Implications for drug delivery and blood flow measurement. J. Natl. Cancer Inst. 86 : 293-299, 1994. – reference: 12) Yamaoka K, Tanigawara Y, Nakagawa T, Uno TA : Pharmacokinetic analysis program (MULTI) for microcomputer, J. Pharmacobio. Dyn. 4 : 879-890, 1981. – reference: 1) Woodle MC, Lasic DD : Sterically stabilized liposomes. Biochim. Biophys. Acta 1113 : 171-199, 1992. – reference: 3) Huang SK, Mayhew R, Gilani S, Lasic DD, Martin FJ, Papahadjopoulos D : Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon carcinoma. Cancer Res. 52 : 6774-6781, 1992. – reference: 2) Papahadjopoulos D, Allen TM, Gabizon A, Mayhew E, Matthay K, Huang SK, Lee K-D, Woodle MC, Lasic DD, Redemann C, Martin FJ : Sterically stabilized liposomes : Improvements in pharmacokinetics and antitumor therapeutic efficacy. Proc. Natl. Acad. Sci. USA 88 : 11460-11464, 1991. – reference: 7) Bjorkman S, Stanski DR, Verotta D, Harashima H : Comparative tissue concentration profile of fentanyl and alfentanil in humans predicted from tissue/blood partition data obtained in rats. Anesthesiology 72 : 865-873, 1990. – reference: 14) Yamaoka K, Nakagawa TA : Nonlinear least squares program based on differential equations, MULTI (RUNGE), for microcomputers. J. Pharmacobio. Dyn. 6 : 595-606, 1983. – reference: 11) Rahman A, Carmichael D, Harris M, Roh JK : Comparative pharmacokinetics of free doxorubicin and doxorubicin entrapped in cardiolipin liposomes. Cancer Res. 46 : 2295-2299, 1986. – reference: 20) Hori K, Zhang Qui-H, Saito S, Tanda S, Li Hao-C, Suzuki M : Microvascular mechanisms of change in tumor blood flow elicited by vasopressors. Jpn. J. Cancer Chemother. 21 : 403-408, 1994. – reference: 5) Fischl MA, Krown SE, O'Boyle KP, Mitsuyasu R, Miles S, Wernz JC, Volberding PA, Kahn J, Groopman JE, Feinberg J, Woody M, the AIDS Clinical Trials Group : Weekly doxorubicin in the treatment of patients with AIDS-related Kaposi's sarcoma. J. Acquir. Immune Defic. Syndr. 6 : 259-264, 1993. – reference: 6) Sawada Y, Harashima H, Hanano M, Sugiyama Y, Iga T : Prediction of the plasma concentration time courses of various drugs in humans based on data from rats. J. Pharmacobio. Dyn. 8 : 757-766, 1985. – reference: 13) Mayer LD, Bally MB, Cullis PR, Wilson SL, Emerman JT : Comparison of free and liposome encapsulated doxorubicin tumor drug uptake and antitumor efficacy in the SC115 murine mamary tumor. Cancer Let. 53 : 183-190, 1990. – reference: 16) Milano G, Cassuto-Viguier E, Fischel JL, Formento P, Renee N, Frenay M, Thyss A, Namer M : Doxorubicin weekly low dose administration : in vitro cytotoxicity generated by the typical pharmacokinetic profile. Eur. J. Cancer 28A : 1881-1885, 1992. – reference: 15) Uchiyama K, Nagayasu A, Yamagiwa Y, Nishida T, Harashima H, Kiwada H : Effects of the size and fluidity of liposomes on their accumulation in tumors : A presumption of their interaction with tumors. Int. J. Pharm. 121 : 195-203, 1995. – reference: 8) Wada DR, Harashima H, Ebling WF, Osaki EW, Stanski DR : Effects of thiopental on regional blood flows in the rat. Anesthesiology 84 : 596-604, 1996. |
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| Subtitle | 生理学的モデルに基づいたシミュレーションスタディ |
| Title | リポソームによる抗癌剤の抗腫瘍効果の最適化に関する速度論的研究 |
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